<i>STAT3</i> overexpression bypasses the tumor inhibition function of <i>miR-124</i>.

<p>(A) SW480 cells were transfected with <i>Pre-miR-124</i> and/or <i>STAT3</i> expression vector, and cell growth was determined by WST1 assay. (B) <i>STAT3</i> overexpression promotes growth of colon cancer cells transfected with <i>Pre-miR-124</i> in nude mice. (C) Tumor weight at the end of the study. Columns, mean of three independent experiments; Bars, SD, **, P<0.01.