<p>(<b>A</b>). Averaged fEPSP time courses of the LTD experiments in which the 10-minutes, 10 Hz protocol was applied to slices from control (blue; n = 12 at 6 mice) and cKO mice (red; n = 10 at 5 mice). Stimulation is indicated by the arrow. Right panel: sample traces are representative of averaged fEPSP’s (from six recordings) recorded before (1) and after (2) 10 Hz stimulation. (<b>B</b>). Scatter plots showed a significant change of %fEPSP between control and cKO mice (**p<0.01, Student's t-test). The average magnitude of LTD was assessed 20 minutes after stimulation. fEPSP amplitudes are expressed as percent of the baseline amplitude.</p
<p><i>(A)</i> Whole-cell patch clamp recordings were made from CA1 pyramidal neurons in hippocampal ...
<p>LTP was evoked in a group of control mice (n = 10) by the presentation of two successive HFS sess...
<p>(<b>a</b>) Representative fEPSP traces before (gray) and after (black) TBS stimulation (top row)....
<p>(A), LFS-induced LTD. Upper plot, LTD was induced by LFS protocol (1 Hz, 900 pulses) at the CA1 d...
<p>(<b>A</b>) A slight increase in LTP was seen in the 100 Hz stimulation protocol in the Tg-GluN2B<...
<p>(<b>A</b>) No changes from the wild-type hippocampal slices were seen in the LTP of the Tg-GluN2D...
<p>A. Slightly enhanced LTP seen in the Tg-GluN2A<sup>2B(CT)</sup> mice with a 1 s 100 Hz stimulatio...
<p>Comparison of averaged LTP expressed as percent change in the slope of fEPSP <i>vs</i> time, indu...
<p>(A) Representative fEPSP traces from hippocampal slices of 9-month old Hu18/18 and Hu97/18 mice i...
<p>(<b>A</b>) Comparison of PPF in 6-month-old mice. The upper channel shows the typical fEPSP trace...
Input/Output (I/O) and LTP changes were measured in both groups. (A) Representative I/O curves for b...
<p>(A) LTD responses induced in L5PyNs from129/Sv mice recorded for 15 min, 30 min, 45 min and 60 mi...
<p>(A, B) 12 TBS-induced L-LTP was reversed by PKMζ inhibitor ZIP. Field EPSP (fEPSP) was evoked in ...
<p>(A) EPSP slope input/output curves were significantly different (p<0.001; n = 9). (B) Paired puls...
<p><b>A</b>: A priming stimulus (10 Hz; small arrow) applied 20–30 min prior to TBS (large arrow) si...
<p><i>(A)</i> Whole-cell patch clamp recordings were made from CA1 pyramidal neurons in hippocampal ...
<p>LTP was evoked in a group of control mice (n = 10) by the presentation of two successive HFS sess...
<p>(<b>a</b>) Representative fEPSP traces before (gray) and after (black) TBS stimulation (top row)....
<p>(A), LFS-induced LTD. Upper plot, LTD was induced by LFS protocol (1 Hz, 900 pulses) at the CA1 d...
<p>(<b>A</b>) A slight increase in LTP was seen in the 100 Hz stimulation protocol in the Tg-GluN2B<...
<p>(<b>A</b>) No changes from the wild-type hippocampal slices were seen in the LTP of the Tg-GluN2D...
<p>A. Slightly enhanced LTP seen in the Tg-GluN2A<sup>2B(CT)</sup> mice with a 1 s 100 Hz stimulatio...
<p>Comparison of averaged LTP expressed as percent change in the slope of fEPSP <i>vs</i> time, indu...
<p>(A) Representative fEPSP traces from hippocampal slices of 9-month old Hu18/18 and Hu97/18 mice i...
<p>(<b>A</b>) Comparison of PPF in 6-month-old mice. The upper channel shows the typical fEPSP trace...
Input/Output (I/O) and LTP changes were measured in both groups. (A) Representative I/O curves for b...
<p>(A) LTD responses induced in L5PyNs from129/Sv mice recorded for 15 min, 30 min, 45 min and 60 mi...
<p>(A, B) 12 TBS-induced L-LTP was reversed by PKMζ inhibitor ZIP. Field EPSP (fEPSP) was evoked in ...
<p>(A) EPSP slope input/output curves were significantly different (p<0.001; n = 9). (B) Paired puls...
<p><b>A</b>: A priming stimulus (10 Hz; small arrow) applied 20–30 min prior to TBS (large arrow) si...
<p><i>(A)</i> Whole-cell patch clamp recordings were made from CA1 pyramidal neurons in hippocampal ...
<p>LTP was evoked in a group of control mice (n = 10) by the presentation of two successive HFS sess...
<p>(<b>a</b>) Representative fEPSP traces before (gray) and after (black) TBS stimulation (top row)....