<p>GABA neurons show the same pattern of modulation as DA neurons. (<b>a</b>) The phasic response to the reward cue of increasing GABA neurons (<i>n</i> = 68) was higher for the second half of FT60 sessions than it was for the first half. Decreasing GABA neurons (<i>n</i> = 138) showed the opposite pattern. The phasic response of unmodulated neurons (<i>n</i> = 66) did not change. Modulation of the phasic response was reduced by pre-feeding (<b>b</b>; <i>n</i> = 15 increasing, 24 decreasing, 33 unmodulated) and eliminated during extinction (<b>c</b>; <i>n</i> = 7 increasing, 4 decreasing, 73 unmodulated). The phasic response of increasing neurons was nearly abolished following pre-feeding and during extinction, and the phasic response of de...
Stimulus-specific adaptation (SSA) is the ability of some neurons to respond better to rare than to ...
<p>(A, Left) Representative voltage-clamp traces of monosynaptic extracellularly evoked pairs of IPS...
<p><b><i>A</i></b>, Puff application of a selective GABA<sub>A</sub>R agonist muscimol (10 µM) evoke...
<p>To compare the basal activity and mean responses between the classes we examined the responses of...
<p>To compare the magnitude of the satiety effect to the magnitude of the mean response, we plotted ...
<p>Motivational modulation of DA and GABA activity in SN. (<b>a</b>) Sample PSTH illustrating the mo...
<p>(A, C, E) Evolution of the response pattern (abscissa) during the course of the experiment (ordin...
<p>(A–C) Dot rasters showing the effect of gabazine on the responses of a neuron. The protocol was t...
<p>(<b>a</b>) Activity of neurons that increased following reward cue normalized to the maximum firi...
<p>(A–C) Dot rasters showing the typical effect of gabazine on the responses of a neuron. A sequence...
<p>(A) Example current clamp traces from cytochemically identified GABA neuron lacking a response to...
<p><b><i>A,</i></b> Average IPSC traces of one NL neuron (E16–17) in response to train stimulations ...
<p>of the response of a dopamine neuron to the cue in FT60 (<b>a</b>), pre-feed (<b>b</b>), and exti...
<div><p>A. Bar graph comparing the mean GABA-evoked current densities (V<sub>h</sub> = -70mV) for co...
<p>In BLA projection neurons, NPS stimulates GABA-mediated synaptic activity dependent on action pot...
Stimulus-specific adaptation (SSA) is the ability of some neurons to respond better to rare than to ...
<p>(A, Left) Representative voltage-clamp traces of monosynaptic extracellularly evoked pairs of IPS...
<p><b><i>A</i></b>, Puff application of a selective GABA<sub>A</sub>R agonist muscimol (10 µM) evoke...
<p>To compare the basal activity and mean responses between the classes we examined the responses of...
<p>To compare the magnitude of the satiety effect to the magnitude of the mean response, we plotted ...
<p>Motivational modulation of DA and GABA activity in SN. (<b>a</b>) Sample PSTH illustrating the mo...
<p>(A, C, E) Evolution of the response pattern (abscissa) during the course of the experiment (ordin...
<p>(A–C) Dot rasters showing the effect of gabazine on the responses of a neuron. The protocol was t...
<p>(<b>a</b>) Activity of neurons that increased following reward cue normalized to the maximum firi...
<p>(A–C) Dot rasters showing the typical effect of gabazine on the responses of a neuron. A sequence...
<p>(A) Example current clamp traces from cytochemically identified GABA neuron lacking a response to...
<p><b><i>A,</i></b> Average IPSC traces of one NL neuron (E16–17) in response to train stimulations ...
<p>of the response of a dopamine neuron to the cue in FT60 (<b>a</b>), pre-feed (<b>b</b>), and exti...
<div><p>A. Bar graph comparing the mean GABA-evoked current densities (V<sub>h</sub> = -70mV) for co...
<p>In BLA projection neurons, NPS stimulates GABA-mediated synaptic activity dependent on action pot...
Stimulus-specific adaptation (SSA) is the ability of some neurons to respond better to rare than to ...
<p>(A, Left) Representative voltage-clamp traces of monosynaptic extracellularly evoked pairs of IPS...
<p><b><i>A</i></b>, Puff application of a selective GABA<sub>A</sub>R agonist muscimol (10 µM) evoke...