EF24 inhibits prostate cancer tumor xenograft growth <i>in vivo</i>.

<p>(A,B) NSG mice were injected subcutaneously with 10⁶ DU145 cells, and after tumor engraftment mice were injected daily with EF24 (200 µg/kg body weight). (A) Tumor growth was determined by bioluminescent imaging of mice injected with luciferin (solid line) or by caliper measurements (dashed line) (n = 8). (B) At necropsy tumors were weighed, or (C) RNA was extracted from tumor tissue and subjected to gene expression analysis by qPCR as indicated (n = 3).