EF24 treatment inhibits the tumorigenic potential of B16 melanoma cells <i>in vivo</i>.

<p>Mice were injected with 10⁶ B16 cells into the tail vein and after 1 week were injected daily with EF24 (200 µg/kg body weight). (A) Bioluminescent imaging of mice injected with luciferin performed at the indicated days, and (B) Kaplan-Meier analysis of survival data (n = 8). (C) RNA was extracted from tumor tissue at necropsy and subjected to gene expression analysis by qPCR as indicated (n = 3). (C) Lungs of control and EF24 treated mice at necropsy (17 days post-tail vein injection).