<p>Immunostaining for the endothelial cell marker, CD31 revealed that <i>OEC</i> (<b>A–C1</b>) and <i>ORt</i> (<b>D–F</b>) fate mapping does not result in Cre reporter expression in endothelial cells, but in a perivascular stromal cell population associated with vascular sinuses of the bone marrow. (<b>A, A1,</b> and <b>D</b>) Cre reporter expression (shown in red). (<b>B, B1,</b> and <b>E</b>) CD31 immunostaining (shown in green). (<b>C, C1,</b> and <b>F</b>) Overlay showing association of Cre reporter expressing cells with bone marrow vasculature.</p
ObjectivesThis study aimed to determine if CD31 is a novel marker of a circulating angio-vasculogeni...
<p>(A–C) Confocal images of EGFP (A), tdTomato (B), and αSMA (C) on longitudinal sections of tibias ...
<p>(<b>A</b>) FACS analysis of <i>cx<sub>3</sub>cr1</i><sup>gfp</sup> cells purified by FACSAria Cel...
<p>Cre reporter expression activated by <i>OEC</i> (<b>A–C1</b> and <b>G–L</b>) and <i>ORt</i> (<b>D...
<p>(<b>A–C</b>) In addition to activating Cre reporter expression (shown in white) in cells of the o...
<p>(<b>A</b>) The intercross of <i>Osterix</i>-Cre mice with <i>Ai9</i> Cre reporter mice generates ...
<div><p>We have carried out fate mapping studies using <i>Osterix</i>-EGFPCre and <i>Osterix</i>-Cre...
We have carried out fate mapping studies using Osterix-EGFPCre and Osterix-CreERt animal models and ...
<p><i>OEC</i> (<b>A–F</b>) and <i>ORt</i> (<b>G–I</b>) activated <i>Ai9</i> Cre reporter expression ...
<p><i>OEC</i> (<b>A-i2</b>) and <i>ORt</i> (<b>J–L</b>) activated <i>Ai9</i> Cre reporter expression...
Rationale: Bone marrow (BM) cells play an important role in physiological and therapeutic neovascula...
Osterix (Osx or Sp7) is a zinc-finger-family transcriptional factor essential for osteoblast differe...
Cancer-associated fibroblasts (CAFs) are a heterogeneous population of mesenchymal cells supporting ...
Haematopoiesis is the process of blood production arising from haematopoietic stem cells (HSCs) that...
Under normal conditions, the great majority of hematopoietic stem cells (HSCs) reside in the bone ma...
ObjectivesThis study aimed to determine if CD31 is a novel marker of a circulating angio-vasculogeni...
<p>(A–C) Confocal images of EGFP (A), tdTomato (B), and αSMA (C) on longitudinal sections of tibias ...
<p>(<b>A</b>) FACS analysis of <i>cx<sub>3</sub>cr1</i><sup>gfp</sup> cells purified by FACSAria Cel...
<p>Cre reporter expression activated by <i>OEC</i> (<b>A–C1</b> and <b>G–L</b>) and <i>ORt</i> (<b>D...
<p>(<b>A–C</b>) In addition to activating Cre reporter expression (shown in white) in cells of the o...
<p>(<b>A</b>) The intercross of <i>Osterix</i>-Cre mice with <i>Ai9</i> Cre reporter mice generates ...
<div><p>We have carried out fate mapping studies using <i>Osterix</i>-EGFPCre and <i>Osterix</i>-Cre...
We have carried out fate mapping studies using Osterix-EGFPCre and Osterix-CreERt animal models and ...
<p><i>OEC</i> (<b>A–F</b>) and <i>ORt</i> (<b>G–I</b>) activated <i>Ai9</i> Cre reporter expression ...
<p><i>OEC</i> (<b>A-i2</b>) and <i>ORt</i> (<b>J–L</b>) activated <i>Ai9</i> Cre reporter expression...
Rationale: Bone marrow (BM) cells play an important role in physiological and therapeutic neovascula...
Osterix (Osx or Sp7) is a zinc-finger-family transcriptional factor essential for osteoblast differe...
Cancer-associated fibroblasts (CAFs) are a heterogeneous population of mesenchymal cells supporting ...
Haematopoiesis is the process of blood production arising from haematopoietic stem cells (HSCs) that...
Under normal conditions, the great majority of hematopoietic stem cells (HSCs) reside in the bone ma...
ObjectivesThis study aimed to determine if CD31 is a novel marker of a circulating angio-vasculogeni...
<p>(A–C) Confocal images of EGFP (A), tdTomato (B), and αSMA (C) on longitudinal sections of tibias ...
<p>(<b>A</b>) FACS analysis of <i>cx<sub>3</sub>cr1</i><sup>gfp</sup> cells purified by FACSAria Cel...