<p>(a) A mixture of HUVEC<sup>FLuc</sup> (3 x 10<sup>5</sup>) and human MSC (7.5 x 10<sup>4</sup>) were embedded in supplemented BME (150 µl) and inoculated subcutaneously in the ventral area (right lower quadrant) of immunodeficient mice. Human vascularized BME-rich organoids were easily identified as small bumps under the skin at all times <i>in vivo</i>. (b) Ventral D-luciferin-based F<sup>Luc</sup>-BLI images of a representative mouse 1, 2, 4, 7, 10 and 13 weeks after implantation of the human vascularized BME-rich organoid. (c) Low magnification (4x) micrograph displaying the entire organoid (Scale bar is 1 mm). Hematoxylin and eosin (H and E)-stained sections taken from different part of the organoids revealed the presence of numerous...
Purpose: Investigate vascular neotissue formation in vivo within human tissue-engineered arterial gr...
<p><b>A</b>, Scheme showing seeding of human-GBM cells (grey spots) onto mouse brain slices. <b>B</b...
<p>(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F...
<p>(a) Supplemented BME (150 μl) was inoculated subcutaneously in the ventral area (left lower quadr...
The aim of this study was to vascularize brain organoids with a patient's own endothelial cells (ECs...
<p>Weight of the Thymus (A), Spleen (B) and Mesenteric Lymph node (C) of control, A238L and mutA238L...
Blood vessel organoids are an important in vitro model to understand the underlying mechanisms of hu...
Organoids derived from human pluripotent stem cells are interesting models to study mechanisms of mo...
Vascularization of tissues, organoids and organ-on-chip models has been attempted using endothelial ...
International audienceExperimental studies of the in vivo behaviour of human cells and tissues have ...
<p>(<b>A-D</b>) Representative photomicrographs of human dermal microvascular endothelial cells (HDM...
Pluripotent stem cell-derived organoids have transformed our ability to recreate complex three-dimen...
Abstract Organoids are biomimetic tissue analogs that are generated via the self‐organization of ste...
Background: Immunodeficient mouse models that accept human cell and tissue grafts can contribute gre...
<p>CD31 (in red) staining of whole-mounted tail skin (A) and ear (C and E). Lifeact-EGFP: green. (B ...
Purpose: Investigate vascular neotissue formation in vivo within human tissue-engineered arterial gr...
<p><b>A</b>, Scheme showing seeding of human-GBM cells (grey spots) onto mouse brain slices. <b>B</b...
<p>(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F...
<p>(a) Supplemented BME (150 μl) was inoculated subcutaneously in the ventral area (left lower quadr...
The aim of this study was to vascularize brain organoids with a patient's own endothelial cells (ECs...
<p>Weight of the Thymus (A), Spleen (B) and Mesenteric Lymph node (C) of control, A238L and mutA238L...
Blood vessel organoids are an important in vitro model to understand the underlying mechanisms of hu...
Organoids derived from human pluripotent stem cells are interesting models to study mechanisms of mo...
Vascularization of tissues, organoids and organ-on-chip models has been attempted using endothelial ...
International audienceExperimental studies of the in vivo behaviour of human cells and tissues have ...
<p>(<b>A-D</b>) Representative photomicrographs of human dermal microvascular endothelial cells (HDM...
Pluripotent stem cell-derived organoids have transformed our ability to recreate complex three-dimen...
Abstract Organoids are biomimetic tissue analogs that are generated via the self‐organization of ste...
Background: Immunodeficient mouse models that accept human cell and tissue grafts can contribute gre...
<p>CD31 (in red) staining of whole-mounted tail skin (A) and ear (C and E). Lifeact-EGFP: green. (B ...
Purpose: Investigate vascular neotissue formation in vivo within human tissue-engineered arterial gr...
<p><b>A</b>, Scheme showing seeding of human-GBM cells (grey spots) onto mouse brain slices. <b>B</b...
<p>(A, C, E, F, G) Axial and longitudinal sections of vessels of (A, B) naïve frozen, or (C, D, E, F...