<p>(A) Evaluation of HIF-1α and CTGF mRNA expression in WKY and SHR left ventricular tissue, as evaluated by Real Time PCR and normalization to 18S expression. Bars represent the mean±SD of 5 experiments for each group. (○), (•) p<0.05 for the expression in SHR vs WKY. (B) Evaluation of HIF-1α and CTGF protein expression in WKY and SHR ventricular tissue, protein expressions were normalized to β-tubulin. Percentage changes were evaluated as mean±SD of 5 experiments for each group. (○), (•) p<0.05 for the expression in SHR vs WKY.</p
Intramyocardial mRNA levels of TSG-6, VEGF, and HGF were significantly higher in HMGB1 group compare...
<p>A, Gene expression levels of TGFβ1 normalized to those of β-actin at 24 hr after H<sub>2</sub>O<s...
<p>(A) TGF-β1 and (B) bFGF protein expression of the supernatant in rat isolated left ventricular ca...
<p>(A) Evaluation of HIF-1α, GPER and CTGF mRNA expression by real time PCR in normoxic and hypoxic ...
<p>(A) Evaluation of HIF-1α and CTGF mRNA expression in WKY left ventricular tissues perfused with v...
<p>A, TGFβ1. B, CTGF. C, BNP. D, ANP. E, Nox2. F, Nox4. G, collagen 1. H, collagen 3. Gene expressio...
<p>Graphs show selected HIF-1α-dependent genes expression in whole hearts in control (C) and at diff...
<p>(A) Western blot analysis of CTGF protein. The GAPDH blot represented here is the same used for v...
<p>(A) HIFα mRNA levels were determined by real-time RT-PCR. Relative fold induction for HIFα mRNA (...
<p>Representative RT-PCR (panel A) and Western Blots (panel B) and relative densitometry for hypoxia...
To get insights into the principles of gene expression changes during cardiac hypertrophy, three rat...
The transforming growth factorβ(TGFβ) superfamily plays an important role in the myocardial response...
<p>Results were normalized by 18S expression levels. Data are mean ± S.E.M. *p<0.05 vs. SHAM group; ...
<p>(A) ERα, ERβ and GPER mRNA expression in WKY and SHR left ventricular tissue, as evaluated by Rea...
<p>i. Box-plot of mRNA expression, showing a significant increase over CTL (n = 6, p = 0.035); ii. r...
Intramyocardial mRNA levels of TSG-6, VEGF, and HGF were significantly higher in HMGB1 group compare...
<p>A, Gene expression levels of TGFβ1 normalized to those of β-actin at 24 hr after H<sub>2</sub>O<s...
<p>(A) TGF-β1 and (B) bFGF protein expression of the supernatant in rat isolated left ventricular ca...
<p>(A) Evaluation of HIF-1α, GPER and CTGF mRNA expression by real time PCR in normoxic and hypoxic ...
<p>(A) Evaluation of HIF-1α and CTGF mRNA expression in WKY left ventricular tissues perfused with v...
<p>A, TGFβ1. B, CTGF. C, BNP. D, ANP. E, Nox2. F, Nox4. G, collagen 1. H, collagen 3. Gene expressio...
<p>Graphs show selected HIF-1α-dependent genes expression in whole hearts in control (C) and at diff...
<p>(A) Western blot analysis of CTGF protein. The GAPDH blot represented here is the same used for v...
<p>(A) HIFα mRNA levels were determined by real-time RT-PCR. Relative fold induction for HIFα mRNA (...
<p>Representative RT-PCR (panel A) and Western Blots (panel B) and relative densitometry for hypoxia...
To get insights into the principles of gene expression changes during cardiac hypertrophy, three rat...
The transforming growth factorβ(TGFβ) superfamily plays an important role in the myocardial response...
<p>Results were normalized by 18S expression levels. Data are mean ± S.E.M. *p<0.05 vs. SHAM group; ...
<p>(A) ERα, ERβ and GPER mRNA expression in WKY and SHR left ventricular tissue, as evaluated by Rea...
<p>i. Box-plot of mRNA expression, showing a significant increase over CTL (n = 6, p = 0.035); ii. r...
Intramyocardial mRNA levels of TSG-6, VEGF, and HGF were significantly higher in HMGB1 group compare...
<p>A, Gene expression levels of TGFβ1 normalized to those of β-actin at 24 hr after H<sub>2</sub>O<s...
<p>(A) TGF-β1 and (B) bFGF protein expression of the supernatant in rat isolated left ventricular ca...