The expression of genes related to mitochondrial function under the TAC operation.

<p>The expression of genes related to mitochondrial energy metabolism was decreased in NTg mice with TAC. The genes presented here are (<b>A</b>) transcriptional regulators, (<b>B</b>) fatty acid metabolism, (<b>C</b>) the TCA cycle, and (<b>D</b>) mitochondria. Pgam2 overexpression further decreased the expression of some of these genes, such as ERRα, Tfam, MCAD, Cox5a, and Cox7a1 with TAC. Values are the mean ± SEM. N: NTg mice. P: Pgam2 mice. *p<0.05 versus the same genotype with the sham operation. †p<0.05 versus NTg mice with the same operation. Sham-operated NTg mice: n = 8; sham-operated Pgam2 mice: n = 8; NTg mice with TAC: n = 10; Pgam2 mice with TAC: n = 14.