IL-10 inhibits LPS induction of pri-miR-155 and miR-155 expression in macrophages.

<p>(A) RAW264.7 parental cells or (B) perimacs were stimulated with LPS +/− IL-10 for the indicated times prior to total RNA extraction. Expression levels of pri-miR-155 and miR-155 were determined by real time PCR and plotted relative to unstimulated samples. Statistical significance between LPS and LPS+IL-10 treatment was calculated by a two-way ANOVA test with a 95% confidence (*<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001). Results were observed in at least three independent experiments.