Treg from HIV-infected individuals suppress anti-hCMV immune response.

<p>Total rectal cells or Treg depleted were stimulated with 10 μg/mL hCMV pp65-peptide pool in presence of anti-CD28/ CD49d. A) Representative example of intracellular IFN-γ by CD4⁺ T-cells(top) and CD107a expression by CD8⁺ T-cells (bottom). B) and C) IFN-γ production by CD4⁺ T-cells from gut and PBMC, respectively. D) and E) CD107a expression in CD8⁺ T-cells on gut and PBMC, respectively.