Genomic structure of the <i>NetAB</i> locus and encoded products.

<p>(<b>A</b>) Schematic view of the <i>NetAB</i> chromosome indicating approximate positions of background mutations believed to be enhancing or suppressing viability of the <i>NetAB</i> deletion. The approximate region of the chromosome exchanged by recombination is indicated by gray shading. (<b>B</b>) Diagram illustrating the location of the <i>hog</i> gene within the <i>NetB</i> gene, as well as the position of the <i>KG03586</i> transposon near the 5’ end of the hog gene. Filled boxes are exons and diagonal lines represent splicing to the mature gene products. (<b>C</b>) Predicted protein product of the <i>hog</i> gene aligned to homologous genes from other <i>Drosophila</i> species. Conserved residues are boxed. The consensus sequence for an FHA domain is shown underneath (pfam00498; cd00060). Identity of additional genes: Ds1: <i>Drosophila</i><i>simulans</i><i>GD15843</i>; Dy1: <i>Drosophila</i><i>yakuba</i><i>GE16495</i>; De1: <i>Drosophila</i><i>erecta</i><i>GG17709</i>; Da1: <i>Drosophila</i><i>ananassae</i><i>GF19383</i>; Dm2 = <i>Drosophila melanogaster CG34323</i>/<i>IP18436p</i>.