Protective efficacy of subunit vaccine candidates against <i>M. tuberculosis</i> infection.
- Qi Xin (429501)
- Hongxia Niu (446309)
- Zhi Li (72309)
- Guoping Zhang (211879)
- Lina Hu (277862)
- Bingxiang Wang (73467)
- Jingjing Li (7654)
- Hongjuan Yu (446310)
- Wanbo Liu (446311)
- Yue Wang (65477)
- Zejiao Da (446312)
- Ruiying Li (446313)
- Qiaoyang Xian (446314)
- Yong Wang (12837)
- Ying Zhang (40767)
- Tao Jing (446315)
- Xingming Ma (446316)
- Bingdong Zhu (446317)
Publication date
August 2013
DOIAbstract
<p>The mice received three times of inoculation with the protein vaccine candidates in DDA/Poly(I:C)/Gelatin. The vaccinated mice were challenged with virulent <i>M. tuberculosis</i> 10 weeks after the final vaccination. Six weeks after challenge with virulent <i>M. tuberculosis</i>, the animals were sacrificed, and the numbers of CFU of <i>M. tuberculosis</i> in the lungs (A) and spleens (B) were determined. Results are presented as mean ± SD, <i>n</i> = 4 or 7. <i>p</i> < 0.05 <i>vs</i>. PBS. ** <i>p</i> < 0.05 vs. PBS, EAMM and MH.</p
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