Assessment of cure by benznidazole (Bz) and posaconazole (Ps), administered in monotherapy or sequential combinations, in a murine model of <i>Trypanosoma cruzi</i> infection¹.

1<p>Swiss female (n = 10) weight 20 to 24 g were inoculated with 5×10³ trypomastigotes (Y strain).</p><p>Treatment was initiated at 4^th day after inoculation followed by 10 or 20 daily doses and it was being orally administered.</p>2<p>FBE – fresh blood examination performed before and after cyclophosphamide immunossupression.</p>3<p>PCR assay was performed in the 1^st and 6^th month after treatment.</p>4<p>mpk – milligrams/kilogram/day.</p>5<p>All mice died before 30 days of infection.</p>6<p>All mice had positive results in fresh blood examination.