Pre-post-comparisons of clinical measures, picture ratings, and brain activation.

<p>Comparison of total scores for Y-BOCS <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071863#pone.0071863-Goodman1" target="_blank">[42]</a>, BDI <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071863#pone.0071863-Beck1" target="_blank">[47]</a>, SCL 90-R <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071863#pone.0071863-Franke1" target="_blank">[48]</a>, assessed at the beginning (pre) and at the end of inpatient treatment (post). The ratings for valence, arousal, and coping for individualized symptom provoking pictures, as well as the brain activation (voxel and weighted) were taken at the first (pre) and the third fMRI scan (post). The number of significant voxels (averaged across all 9 patients) of the first and last fMRI measurements were compared separately for eight brain areas (ROIs). Voxel numbers were also relativized for each patient for the brain areas with the largest voxel number, implying that brain areas with larger voxel numbers are weighted more.</p><p>Abbreviations: <i>t</i>: <i>t</i>-values of two-sided <i>t</i>-tests. ISPP: individualized symptom provoking pictures; CC/SMA: anterior cingulate cortex/supplementary motor area; DLPFC r: dorsolateral prefrontal cortex right; DLPFC l: dorsolateral prefrontal cortex left; Insula r: insula right; Insula l: insula left; Parietal r: parietal cortex right; Parietal l: parietal cortex left; cuneus.