<p>Predicted concentrations of ATP (<i>left column</i>), 2,3-BPG (<i>center column</i>), and total HX (<i>right column</i>) at 7, 14, 28, and 35 days after storage in various combinations of ADE and GUO concentrations. In each panel, the x and y axes represent initial concentration of ADE and GUO in the model, respectively. The initial setting of ADE and GUO varied between 0 to 3 mM.</p
<p>Our metabolic network model predicted different adjustments in the biomass composition of wild ty...
<p>A) Cell growth and viability, B) Glucose and lactate concentration profiles, C) Glutamate and mAb...
<p>a) Glucose concentration measured by the Amplex Red ® glucose oxidase assay (gray circles) and gl...
<p><i>Panel A</i>: Time-related changes of metabolic intermediates with or without adenine (ADE) and...
<p><i>Panel A</i>: Time courses of intracellular pH at 37°C (measured values; ▪) and at 4°C (estimat...
Comparison of the predicted concentration ranges for 15 intracellular metabolites in E. coli with ab...
<p>* No lower bounds were imposed on H<sub>2</sub> or formate concentrations, which can fall below 0...
Although intraerythrocytic ATP and 2,3-bisphophoglycerate (2,3-BPG) are known as direct indicators o...
<div><p>Although intraerythrocytic ATP and 2,3-bisphophoglycerate (2,3-BPG) are known as direct indi...
<p><i>Panel A</i>: Transition of enzymatic activities. Each enzymatic activity was represented as a ...
Physiological concentrations of metabolites can partly be explained by their molecular struc-ture. W...
<p>Using the five biomarkers (highlighted in red), the concentration profiles for the remaining 91 m...
Model 1 simulation represents the lactate concentration pre-parameter adjustment with all model para...
Predicted changes of the cytoplasmic NADPH/NADPratio of the unfitted model. The NADPH/NADPratio incr...
<p>This figure depicts the simplified Glycolysis pathway as described by the BioModels model Wolf200...
<p>Our metabolic network model predicted different adjustments in the biomass composition of wild ty...
<p>A) Cell growth and viability, B) Glucose and lactate concentration profiles, C) Glutamate and mAb...
<p>a) Glucose concentration measured by the Amplex Red ® glucose oxidase assay (gray circles) and gl...
<p><i>Panel A</i>: Time-related changes of metabolic intermediates with or without adenine (ADE) and...
<p><i>Panel A</i>: Time courses of intracellular pH at 37°C (measured values; ▪) and at 4°C (estimat...
Comparison of the predicted concentration ranges for 15 intracellular metabolites in E. coli with ab...
<p>* No lower bounds were imposed on H<sub>2</sub> or formate concentrations, which can fall below 0...
Although intraerythrocytic ATP and 2,3-bisphophoglycerate (2,3-BPG) are known as direct indicators o...
<div><p>Although intraerythrocytic ATP and 2,3-bisphophoglycerate (2,3-BPG) are known as direct indi...
<p><i>Panel A</i>: Transition of enzymatic activities. Each enzymatic activity was represented as a ...
Physiological concentrations of metabolites can partly be explained by their molecular struc-ture. W...
<p>Using the five biomarkers (highlighted in red), the concentration profiles for the remaining 91 m...
Model 1 simulation represents the lactate concentration pre-parameter adjustment with all model para...
Predicted changes of the cytoplasmic NADPH/NADPratio of the unfitted model. The NADPH/NADPratio incr...
<p>This figure depicts the simplified Glycolysis pathway as described by the BioModels model Wolf200...
<p>Our metabolic network model predicted different adjustments in the biomass composition of wild ty...
<p>A) Cell growth and viability, B) Glucose and lactate concentration profiles, C) Glutamate and mAb...
<p>a) Glucose concentration measured by the Amplex Red ® glucose oxidase assay (gray circles) and gl...