CD11b expression is induced in human leukemia cell lines upon treatment with PMA.

<p>The THP1 or HL-60 cells were treated with PMA (200 nM) for the indicated periods. The CD11b mRNA expression was determined by qRT-PCR in (A) THP1 and (B) HL-60 cells. The CD11b(+) cells were detected using FITC-labeled CD11b antibody, then analyzed by flow cytometry and expressed as the mean fluorescence intensity in (C) THP1 and (D) HL-60 cells. Data represent the mean ± SD from three independent experiments. *<i>p</i><0.05 and **<i>p</i><0.01 represents significant differences compared with the 0 h group.