<p>Bronchoalveolar lavage (BAL) was obtained from chronic obstructive pulmonary disease (COPD, n = 7), smokers with normal lung function (S, n = 4) and healthy non-smokers (HNS, n = 8). Cells were labelled with anti-CD8 (green) and anti-CD247 (red). Nuclei were counterstained with 4′,6-diamidino-2-phenylindole (DAPI, blue). Top panel: Representative images of COPD BAL cells. Merged image displays a CD8+CD247+ cell (yellow, arrow), a CD8+CD247- cell (green, arrow head) and a CD8-CD247+ (red). Lower panel: Percentage of BAL CD8 cells positive for CD247 in COPD, S and HNS. Statistical significance indicated by *p<0.05. Data was analysed by Kruskall-Wallis test followed by Dunn’s multiple comparisons test if p<0.05.</p
SummaryChronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation in pulm...
Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but th...
<p>(A) Positive reactivity was identified by 3–3′-diaminobenzidine-4HCl (DAB). Bar: 50 µm. (B) Doubl...
Bronchoalveolar lavage (BAL) may have a potential role in contributing to a more precise definition ...
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease; it is a leading...
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease; it is a leading...
<p>a) CD163, b) CD204, c) CD206, *: p<0.01. The Global Initiative for Chronic Obstructive Lung Disea...
© 2017 Nailya Kubysheva et al. The definition of new markers of local and systemic inflammation of c...
Background: The numbers of airway CD8 and B lymphocytes are increased in COPD patients, suggesting a...
ABSTRACT: Chronic obstructive pulmonary disease (COPD) is characterised by an excessive inflammatory...
<p>a) The number of CD68 positive cells and %FEV<sub>1.0</sub> (r = 0.729 and p<0.01), b) The number...
<p>(<b>A–C</b>) NK cells; (<b>D–F</b>) CD56+ T cells. (<b>A</b>) Representative staining for CD8 on ...
<p>*: p<0.01. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) clinical criteria fo...
CD8 cells may contribute towards an autoimmune process in COPD. Down regulation of T cell receptor (...
Chronic obstructive pulmonary disease (COPD) is a worldwide burden and a major cause of death. Patho...
SummaryChronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation in pulm...
Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but th...
<p>(A) Positive reactivity was identified by 3–3′-diaminobenzidine-4HCl (DAB). Bar: 50 µm. (B) Doubl...
Bronchoalveolar lavage (BAL) may have a potential role in contributing to a more precise definition ...
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease; it is a leading...
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease; it is a leading...
<p>a) CD163, b) CD204, c) CD206, *: p<0.01. The Global Initiative for Chronic Obstructive Lung Disea...
© 2017 Nailya Kubysheva et al. The definition of new markers of local and systemic inflammation of c...
Background: The numbers of airway CD8 and B lymphocytes are increased in COPD patients, suggesting a...
ABSTRACT: Chronic obstructive pulmonary disease (COPD) is characterised by an excessive inflammatory...
<p>a) The number of CD68 positive cells and %FEV<sub>1.0</sub> (r = 0.729 and p<0.01), b) The number...
<p>(<b>A–C</b>) NK cells; (<b>D–F</b>) CD56+ T cells. (<b>A</b>) Representative staining for CD8 on ...
<p>*: p<0.01. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) clinical criteria fo...
CD8 cells may contribute towards an autoimmune process in COPD. Down regulation of T cell receptor (...
Chronic obstructive pulmonary disease (COPD) is a worldwide burden and a major cause of death. Patho...
SummaryChronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation in pulm...
Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but th...
<p>(A) Positive reactivity was identified by 3–3′-diaminobenzidine-4HCl (DAB). Bar: 50 µm. (B) Doubl...