Effect of adding control genes (highlighted) as priors on the estimates of fixed effects of stress in the coral dataset.

<p>The points are posterior means, the 95% credible intervals are denoted as dashed lines connecting upper and lower interval limits across genes. (a) Comparison between naïve model (no control genes specified) and two informed models, with one (<i>nd5</i>) or two (<i>nd5, rpl11</i>) control genes specified (the control genes were allowed to change 1.2-fold on average in response to fixed factors). (b) Comparison of the naïve and two-gene informed model to the two-gene fixed model, in which the same control genes were required to be absolutely stable.