<p>An image of LT (200 ng/ml)-induced hemolysis <i>in vitro</i> was compared with a saline-treated control group (A). After peripheral blood cells were incubated with or without LT at 37°C for 2 hours, plasma hemoglobin levels (µg/dL) were measured using Drabkin’s reagent (B). The experimental outline of the <i>in vivo</i> hemolysis assay is shown, in which untreated and saline-treated groups served as negative control groups (C). The RBC counts (D) and the levels of cell-free plasma hemoglobin (E) were determined 22, 44, and 66 hours after the mice were treated with LT. The <i>in vitro</i> erythroid colony-forming cell assay was performed by incubating murine BM cells with or without LT (200 ng/ml or 20 ng/ml). Colonies of progenitor cells...
<p>(A) Hemolytic activity. Fresh RBC suspension was incubated with peptides. The release of hemoglob...
<p><b>A</b>. Mice without xenografts treated with saline or 50, 100, 150 or 250 MBq/kg <sup>177</sup...
<p>The response of RBL in T-cells was determined by MTT assay. (A) The graph shows RBL concentration...
<p>The experimental outlines are indicated (A), (E). Mice were treated with saline (n = 12), G-CSF (...
<p>A) <i>Ex vivo</i> fluorescent microscopy picture of erythrophagocytozing cell in the spleen of <i...
<p>The experimental outline is illustrated in (A). Flow cytometry analyses of BM cells were performe...
<p>Erythrocytes isolated from the blood of mouse (purple line), goat (black line), human (blue line)...
<p>The timetable of <i>in vitro</i> erythrocytic differentiation using human cord blood-derived CD34...
Hemopoiesis was studied in homozygous lactate dehydrogenase (LDH) mutant mice not showing noticeable...
Mitochondria and lysosome have been used to study drug-cell interactions both in vitro and in vivo. ...
<p>The groups were evaluated at (A) 60, (B) 120, (C) 180, and (D) 240 min of incubation. The control...
<p>The erythrocytes were preincubated with APS at the indicated concentrations for 30 min at 37°C. T...
<p>Cytotoxic responses were evaluated by the lactate dehydrogenase (LDH)-releasing method. Splenic T...
<p>Control (Ctrl) and hemin (HE)-treated mice were euthanized 24 h after the last injection with PBS...
<p>Colony forming assays using marrow aspirates from week-3 wild type (WT), collagen X transgenic (T...
<p>(A) Hemolytic activity. Fresh RBC suspension was incubated with peptides. The release of hemoglob...
<p><b>A</b>. Mice without xenografts treated with saline or 50, 100, 150 or 250 MBq/kg <sup>177</sup...
<p>The response of RBL in T-cells was determined by MTT assay. (A) The graph shows RBL concentration...
<p>The experimental outlines are indicated (A), (E). Mice were treated with saline (n = 12), G-CSF (...
<p>A) <i>Ex vivo</i> fluorescent microscopy picture of erythrophagocytozing cell in the spleen of <i...
<p>The experimental outline is illustrated in (A). Flow cytometry analyses of BM cells were performe...
<p>Erythrocytes isolated from the blood of mouse (purple line), goat (black line), human (blue line)...
<p>The timetable of <i>in vitro</i> erythrocytic differentiation using human cord blood-derived CD34...
Hemopoiesis was studied in homozygous lactate dehydrogenase (LDH) mutant mice not showing noticeable...
Mitochondria and lysosome have been used to study drug-cell interactions both in vitro and in vivo. ...
<p>The groups were evaluated at (A) 60, (B) 120, (C) 180, and (D) 240 min of incubation. The control...
<p>The erythrocytes were preincubated with APS at the indicated concentrations for 30 min at 37°C. T...
<p>Cytotoxic responses were evaluated by the lactate dehydrogenase (LDH)-releasing method. Splenic T...
<p>Control (Ctrl) and hemin (HE)-treated mice were euthanized 24 h after the last injection with PBS...
<p>Colony forming assays using marrow aspirates from week-3 wild type (WT), collagen X transgenic (T...
<p>(A) Hemolytic activity. Fresh RBC suspension was incubated with peptides. The release of hemoglob...
<p><b>A</b>. Mice without xenografts treated with saline or 50, 100, 150 or 250 MBq/kg <sup>177</sup...
<p>The response of RBL in T-cells was determined by MTT assay. (A) The graph shows RBL concentration...