<p>Regulation of hnRNP L expression by IFN-γ and hypoxia and the role of the HILDA complex in the <i>VEGFA</i> RNA switch.</p
Hypoxia-Inducible Factor 1alpha (HIF-1alpha) is an important protein in the homeostatic control of g...
<p>This schematic diagram shows HIF-1 binding to the HRE in the WT1 promoter (1; requirement of HIF-...
<p>A, Levels of active β-catenin were determined by western blot at different hypoxia time points fo...
<p>(A) hnRNP A2/B1, DRBP76, and hnRNP L are required for hypoxia-inducible RNA switch activity <i>in...
Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generat...
Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generat...
<p>(A) Recombinant hnRNP L by itself does not drive the <i>VEGFA</i> RNA switch and restore <i>in vi...
Ligand binding to structural elements in noncoding regions of mRNA modulates gene expression1,2. Lig...
<p>(A) Condition-dependent binding of <i>VEGFA</i> mRNA to GAIT and HILDA complexes. U937 cells were...
<p>(A) Rapid degradation of hnRNP L in absence of hnRNP A2/B1. U937 cells were transfected with hnRN...
<p>Influence of HIF–1α knockdown by siRNA in ASCs under hypoxia (A) The relative mRNA expression lev...
<p>(A) Steady-state amount of hnRNP L mRNA is not regulated by IFN-γ. U937 cells were treated with I...
RNA-binding proteins (RBPs) control all steps of mRNA processing, including pre-mRNA splicing, mRNA ...
Cellular messenger RNAs (mRNAs) exist almost exclusively in the context of ribonucleoprotein complex...
Heterogenous nuclear ribonucleoproteins (hnRNPs) are predominantly nuclear and have been shown to be...
Hypoxia-Inducible Factor 1alpha (HIF-1alpha) is an important protein in the homeostatic control of g...
<p>This schematic diagram shows HIF-1 binding to the HRE in the WT1 promoter (1; requirement of HIF-...
<p>A, Levels of active β-catenin were determined by western blot at different hypoxia time points fo...
<p>(A) hnRNP A2/B1, DRBP76, and hnRNP L are required for hypoxia-inducible RNA switch activity <i>in...
Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generat...
Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generat...
<p>(A) Recombinant hnRNP L by itself does not drive the <i>VEGFA</i> RNA switch and restore <i>in vi...
Ligand binding to structural elements in noncoding regions of mRNA modulates gene expression1,2. Lig...
<p>(A) Condition-dependent binding of <i>VEGFA</i> mRNA to GAIT and HILDA complexes. U937 cells were...
<p>(A) Rapid degradation of hnRNP L in absence of hnRNP A2/B1. U937 cells were transfected with hnRN...
<p>Influence of HIF–1α knockdown by siRNA in ASCs under hypoxia (A) The relative mRNA expression lev...
<p>(A) Steady-state amount of hnRNP L mRNA is not regulated by IFN-γ. U937 cells were treated with I...
RNA-binding proteins (RBPs) control all steps of mRNA processing, including pre-mRNA splicing, mRNA ...
Cellular messenger RNAs (mRNAs) exist almost exclusively in the context of ribonucleoprotein complex...
Heterogenous nuclear ribonucleoproteins (hnRNPs) are predominantly nuclear and have been shown to be...
Hypoxia-Inducible Factor 1alpha (HIF-1alpha) is an important protein in the homeostatic control of g...
<p>This schematic diagram shows HIF-1 binding to the HRE in the WT1 promoter (1; requirement of HIF-...
<p>A, Levels of active β-catenin were determined by western blot at different hypoxia time points fo...
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