M-currents in sympathetic neurons from adult <i>KCNQ2+/</i>− mice.

<p><b>A</b>: mean M-current density (pA.pF⁻¹) in wild-type (+/+) and KCNQ2<b><i>+/</i></b>− neurons. <b>B:</b> current enhancement by 10 µM retigabine, measured as % increase in standing outward current at −20 mV (see Fig. 3). <b>C:</b> mean % inhibition of wild-type (+/+) and <i>KCNQ2+/</i>− M-current by increasing concentrations of tetraethylammonium (TEA, mM). Vertical bars: SEM; numbers of neurons tested in brackets. * – indicates significant difference from wild type (P<0.005).