<p>(A) <u>Summary of liver Treg FACS analysis</u>. Liver immune cells were stained for CD4, CD25 and intranuclear FoxP3. Shown is the percentage of the CD4<sup>+</sup> population that were CD25<sup>+</sup>Foxp3<sup>+</sup> (mean ±SD). *P<.001 vs. Ig-α<sup>-/-</sup> BSS; #P < .001 vs. Ig-α<sup>-/-</sup> RRV. (B) <u>Representative Tregs dot plots</u>. Shown are representative flow cytometry dot plots of liver Tregs (gated on CD4<sup>+</sup> cells).</p
<p>Foxp3-GFP mice were intraperitoneally infected (or not) with Pc-iRBCs. All animals were divided i...
<p>T cells were isolated from the spleens of 6–8 week-old WT and <i>Ifng</i><sup>-/-</sup> mice via ...
<p>(<b>A</b>) Schematic diagram depicts depletion of CD4 and CD8 T cells via treatment with monoclon...
<p>(A) <u>Liver immune cell profile in 2 week old mice</u>. Immune cells were identified based on CD...
<p>4x10<sup>6</sup> CD8 OT-I T cells were transferred intravenously into TF-OVA mice. Non-parenchyma...
<p>Foxp3-GFP or CD11c-YFP mice were intraperitoneally infected or not with Pc-iRBCs. All animals wer...
<p>Flow cytometry analysis of CD4<sup>+</sup>Foxp3<sup>+</sup> and CD8<sup>+</sup>Foxp3<sup>+</sup> ...
<p>(A) CFSE-labeled CD8 OT-I T cells were stimulated by APCs isolated from spleens of TF-OVA mice fo...
<p>(A) <u>Successful depletion of Tregs in Ig-α <sup>-/-</sup> mice</u>. PC61 (anti-CD25 depleting a...
<div><p>Background</p><p>The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease ...
The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease is still under debate. It...
<p>4*10<sup>6</sup> CD8 OT-I T cells were transferred into TF-OVAxDEREG mice at day 0 and day 21 (A–...
<p>(<b>A</b>) Numbers of hepatic mononuclear cells. Data are presented as the mean ± SEM for each gr...
<p>Mice were i.c. infected and analyzed at 3, 7, 10, 14, and 28 dpi as indicated. The percentages of...
CD4 Foxp3 T cells are well-defined regulatory T (TR) cells that develop in the thymus through positi...
<p>Foxp3-GFP mice were intraperitoneally infected (or not) with Pc-iRBCs. All animals were divided i...
<p>T cells were isolated from the spleens of 6–8 week-old WT and <i>Ifng</i><sup>-/-</sup> mice via ...
<p>(<b>A</b>) Schematic diagram depicts depletion of CD4 and CD8 T cells via treatment with monoclon...
<p>(A) <u>Liver immune cell profile in 2 week old mice</u>. Immune cells were identified based on CD...
<p>4x10<sup>6</sup> CD8 OT-I T cells were transferred intravenously into TF-OVA mice. Non-parenchyma...
<p>Foxp3-GFP or CD11c-YFP mice were intraperitoneally infected or not with Pc-iRBCs. All animals wer...
<p>Flow cytometry analysis of CD4<sup>+</sup>Foxp3<sup>+</sup> and CD8<sup>+</sup>Foxp3<sup>+</sup> ...
<p>(A) CFSE-labeled CD8 OT-I T cells were stimulated by APCs isolated from spleens of TF-OVA mice fo...
<p>(A) <u>Successful depletion of Tregs in Ig-α <sup>-/-</sup> mice</u>. PC61 (anti-CD25 depleting a...
<div><p>Background</p><p>The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease ...
The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease is still under debate. It...
<p>4*10<sup>6</sup> CD8 OT-I T cells were transferred into TF-OVAxDEREG mice at day 0 and day 21 (A–...
<p>(<b>A</b>) Numbers of hepatic mononuclear cells. Data are presented as the mean ± SEM for each gr...
<p>Mice were i.c. infected and analyzed at 3, 7, 10, 14, and 28 dpi as indicated. The percentages of...
CD4 Foxp3 T cells are well-defined regulatory T (TR) cells that develop in the thymus through positi...
<p>Foxp3-GFP mice were intraperitoneally infected (or not) with Pc-iRBCs. All animals were divided i...
<p>T cells were isolated from the spleens of 6–8 week-old WT and <i>Ifng</i><sup>-/-</sup> mice via ...
<p>(<b>A</b>) Schematic diagram depicts depletion of CD4 and CD8 T cells via treatment with monoclon...