miR-155^−/− mice are susceptible to hepatic steatosis.

<p>WT or miR-155^−/− mice were fed either normal chow or HFD and livers examined at 24 weeks. (<b>A</b>) Liver weights (g). (<b>B</b>) Gross morphology. (<b>C</b>) Total cholesterol (TC), free cholesterol (FC) and cholesterol ester (CE) measurements in liver (µg/mg of cell protein). (<b>D</b>) Triglyceride measurements in liver (µg/mg of cell protein). (<b>E</b>) Representative H&E, and Oil Red O staining of the livers (40x magnification, scale bar 5 µm). Data are Means ± SEM pooled from 2 independent experiments, n = 13–21 mice/group. ** p<0.01, *** p<0.001 Student’s unpaired <i>t</i>-test compared to WT fed HFD.