Regional ventilation distribution.

<p>Examples of functional EIT scans of regional lung ventilation in animal 2 during all measurement time points (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072675#pone-0072675-g001" target="_blank">Figure 1</a> for explanation). The orientation of the scans is indicated (ant., anterior; post., posterior). Panel A: Ventilated areas within the chest cross-section exhibit higher values of relative impedance change and are shown in red tones. In normal lungs (NL), symmetrical ventilation distribution between the right and left lung regions was found. With induction of acute lung injury (ALI), higher ventilation in the right lung region with pronounced ventilation in its ventral part and reduced left lung ventilation especially in its dorsal part were found. After PEEP was set 2 cm H₂O above the lower inflection point (LIP) according to the pressure-volume curve, a shift in ventilation toward the dependent (dorsal) lung regions was observed. No obvious difference between ventilation with 10 ml/kg V_T and inactive interventional lung assist (ILA) (high V_T, no ILA) and ventilation with 5 ml/kg V_T and active ILA (low V_T, ILA) was detected. Panel B: Ventilation difference scans of the same animal. Red color indicates increase in regional ventilation, blue color shows the decrease in ventilation compared with baseline.