<p>Schematic showing that the stability of a protein of interest (POI) fused to a destabilizing domain (DD) can be controlled using a high-affinity, stabilizing ligand.</p
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
International audienceThe protein-protein interactions (PPIs) of 14-3-3 proteins are a model system ...
Protein stability is often a limiting factor in the development of commercial proteins and biopharma...
Tools that can directly regulate the activity of any protein-of-interest are valuable in the study o...
ABSTRACT Equilibrium binding ligands usually increase protein thermal stability by an amount proport...
AbstractEquilibrium binding ligands usually increase protein thermal stability by an amount proporti...
SummarySmall protein ligands can provide superior physiological distribution compared with antibodie...
Information about the stability of proteins is paramount to determine their optimal storage or react...
Information about the stability of proteins is paramount to determine their optimal storage or react...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
We have developed a strategy for grafting a protein-protein interface based on the known crystal str...
The ability to make specific perturbations to biological molecules in a cell or organism is a centra...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
International audienceThe protein-protein interactions (PPIs) of 14-3-3 proteins are a model system ...
Protein stability is often a limiting factor in the development of commercial proteins and biopharma...
Tools that can directly regulate the activity of any protein-of-interest are valuable in the study o...
ABSTRACT Equilibrium binding ligands usually increase protein thermal stability by an amount proport...
AbstractEquilibrium binding ligands usually increase protein thermal stability by an amount proporti...
SummarySmall protein ligands can provide superior physiological distribution compared with antibodie...
Information about the stability of proteins is paramount to determine their optimal storage or react...
Information about the stability of proteins is paramount to determine their optimal storage or react...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
We have developed a strategy for grafting a protein-protein interface based on the known crystal str...
The ability to make specific perturbations to biological molecules in a cell or organism is a centra...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
Natural compounds are an important class of potent drug molecules including some retrospectively fou...
International audienceThe protein-protein interactions (PPIs) of 14-3-3 proteins are a model system ...