Induction of γ-H2AX foci by HU and GEM in the UACC-1598 ovarian cancer cell line.

<p>A. Representative picture of γ-H2AX foci detected by immunofluorescence and examples of how cells are grouped into different categories based on the degree of DNA damage. DAPI stained DNA is shown in blue and immunofluorescence of γ-H2AX foci is shown in red. B. Percentage of cells in each category based on amount of γ-H2AX foci. The statistical analysis showed the differences of cells in the No signal group vs. all other groups compared to the control cells. ***denotes a <i>P</i> value of <0.001.