The change in effect size with (A) Region of injury, (B) Method of compression (Clip = aneurysm clip), (C) Neurobehavioural score (NDS = Neurologic deficit score; Olby = Olby score; Tarlov = Tarlov scale; Multiple = ≥2 behavioural tests; Motor = Motor test; BBB = Basso Beattie Bresnahan scale).

<p>The shaded gray bar represents the 95% confidence limits of the global estimate. The vertical error bars represent the 95% confidence intervals for the individual estimates. The width of each bar reflects the log of the number of animals contributing to that comparison. Each stratification accounts for a significant proportion of the heterogeneity observed between studies. (D) Meta-regression of functional neurobehavioural improvement versus the time of final assessment (p=0.046). The size of each point reflects the precision of each comparison.