<p>(<b>A</b>) Schematic of a ciliary axoneme cross section, with the N-DRC enlarged (adapted from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072299#pone.0072299-Lin1" target="_blank">[30]</a>). (<b>B</b>) Photomicrographs of CCDC65 immunofluorescent staining in nasal epithelial cells revealing cytoplasmic and axonemal localization of the protein in normal cells compared to decreased expression in epithelial cells collected from the PCD subject (CCDC65, red; acetylated α-tubulin, green; DAP, blue), Scale bar = 10 µm.</p
<p><b>A</b> Ciliary cross sections – magnification 30,000 (patient #181). <i>Left panel</i> – a typi...
<p>(A–C) Immunostaining of control human nasal brush epithelia reveals endogenous HEATR2 (red: Novus...
The normal distal airway epithelium (left) contains multi-ciliated epithelial cells, goblet (mucus-...
<p>Photomicrographs of normal airway epithelial cells following immunofluorescent staining for GAS8,...
<p>Photomicrographs of normal human lung section (<b>A</b>) (scale bar = 100 µm) and bronchial epith...
<div><p>Background</p><p>Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by imp...
BACKGROUND: Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by impaired ciliary...
<p><b>A</b> Representative immunostaining images of βIV-tubulin (βIV-tub, green) and Ctnnb1 (red) in...
A) Fluorescence microscopy of eCFP fused to C20orf26, CCDC147 and IQCA1 in hTERT-RPE1 cells. Acetyla...
Cilia are essential to many diverse cellular processes. Although many major axonemal components have...
<p>When compared to the unstained isotype control (Rabbit IgG) (A), staining identifies moderate cyt...
<p>HAE cells were grown in an air-liquid interface (ALI) culture system until differentiation was ac...
<p>A. Western blots of an enriched ciliary membrane preparation (OC), olfactory epithelium membranes...
<p>PBECs were grown for mucociliary differentiation using ALI cultures and dual-stained for with (A)...
<p>(<b>A</b>) Human CML cells stained with antibodies against acetylated (green) and glutamylated tu...
<p><b>A</b> Ciliary cross sections – magnification 30,000 (patient #181). <i>Left panel</i> – a typi...
<p>(A–C) Immunostaining of control human nasal brush epithelia reveals endogenous HEATR2 (red: Novus...
The normal distal airway epithelium (left) contains multi-ciliated epithelial cells, goblet (mucus-...
<p>Photomicrographs of normal airway epithelial cells following immunofluorescent staining for GAS8,...
<p>Photomicrographs of normal human lung section (<b>A</b>) (scale bar = 100 µm) and bronchial epith...
<div><p>Background</p><p>Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by imp...
BACKGROUND: Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by impaired ciliary...
<p><b>A</b> Representative immunostaining images of βIV-tubulin (βIV-tub, green) and Ctnnb1 (red) in...
A) Fluorescence microscopy of eCFP fused to C20orf26, CCDC147 and IQCA1 in hTERT-RPE1 cells. Acetyla...
Cilia are essential to many diverse cellular processes. Although many major axonemal components have...
<p>When compared to the unstained isotype control (Rabbit IgG) (A), staining identifies moderate cyt...
<p>HAE cells were grown in an air-liquid interface (ALI) culture system until differentiation was ac...
<p>A. Western blots of an enriched ciliary membrane preparation (OC), olfactory epithelium membranes...
<p>PBECs were grown for mucociliary differentiation using ALI cultures and dual-stained for with (A)...
<p>(<b>A</b>) Human CML cells stained with antibodies against acetylated (green) and glutamylated tu...
<p><b>A</b> Ciliary cross sections – magnification 30,000 (patient #181). <i>Left panel</i> – a typi...
<p>(A–C) Immunostaining of control human nasal brush epithelia reveals endogenous HEATR2 (red: Novus...
The normal distal airway epithelium (left) contains multi-ciliated epithelial cells, goblet (mucus-...