Correlation between Aβ aggregation and variations of fluorescence intensity.

<p>(A) Magnified images of center region (100 × 100 pixel) in fluorescence micrographs of QDAβ- Aβ₄₂ coaggregates before (left) and after (right) incubation (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072992#pone-0072992-g001" target="_blank">Figure 1B</a>). (B) Schematic illustrations of the distribution of QDAβ (red) and Aβ₄₂ (gray) molecules before (left) and after (right) incubation of samples. QDAβ molecules are diffused in the sample solution before incubation (left), and QDAβ molecules are inserted in Aβ₄₂ fibrils after incubation (right). (C) The histograms of fluorescence intensities of 10,000 pixels (100 × 100 pixel) before (left) and after (right) incubation of samples.