<p>The overall pathway by which the activation of PAR<sub>2</sub> regulates cell proliferation.</p
SummaryCell polarity plays a key role in the development of the central nervous system (CNS). Intere...
The majority of cancers, such as breast cancer, originate from epithelial structures. Highly organiz...
Understanding the cell type-specific molecular mechanisms by which distinct signaling pathways combi...
Cell proliferation is the process whereby cells reproduce themselves by growing and then dividing in...
<p>Sharp arrows indicate activation/enhancement and blocked arrows indicate inhibition.</p
A key function of signal transduction during cell polarization is the creation of spatially segregat...
Protease-activated receptors PAR1 and PAR(2) play an important role in the control of epithelial cel...
Intricate networks of protein kinases are intimately involved in the regulation of cellular events r...
Representatives shown for the MAPK, PI3K/Akt, and Wnt pathways. In the MAPK pathway, Ras gets activa...
AbstractNowadays, cellular physiology is best understood by analysing their interacting molecular co...
The regulation of mammalian cell proliferation is discussed in relation to the recently proposed 'un...
<p>A549 cells were treated with PAR<sub>2</sub> activating peptide (PAR<sub>2</sub>-AP, 50 µM) or re...
The discovery that phosphorylation of selected proteins by cyclin-dependent kinases is the engine wh...
A ”cancer pathway” is a cellular regulatory system whose activation or inactivation by a...
The G protein-coupled receptor proteinase-activated receptor 2 (PAR2) has been implicated in various...
SummaryCell polarity plays a key role in the development of the central nervous system (CNS). Intere...
The majority of cancers, such as breast cancer, originate from epithelial structures. Highly organiz...
Understanding the cell type-specific molecular mechanisms by which distinct signaling pathways combi...
Cell proliferation is the process whereby cells reproduce themselves by growing and then dividing in...
<p>Sharp arrows indicate activation/enhancement and blocked arrows indicate inhibition.</p
A key function of signal transduction during cell polarization is the creation of spatially segregat...
Protease-activated receptors PAR1 and PAR(2) play an important role in the control of epithelial cel...
Intricate networks of protein kinases are intimately involved in the regulation of cellular events r...
Representatives shown for the MAPK, PI3K/Akt, and Wnt pathways. In the MAPK pathway, Ras gets activa...
AbstractNowadays, cellular physiology is best understood by analysing their interacting molecular co...
The regulation of mammalian cell proliferation is discussed in relation to the recently proposed 'un...
<p>A549 cells were treated with PAR<sub>2</sub> activating peptide (PAR<sub>2</sub>-AP, 50 µM) or re...
The discovery that phosphorylation of selected proteins by cyclin-dependent kinases is the engine wh...
A ”cancer pathway” is a cellular regulatory system whose activation or inactivation by a...
The G protein-coupled receptor proteinase-activated receptor 2 (PAR2) has been implicated in various...
SummaryCell polarity plays a key role in the development of the central nervous system (CNS). Intere...
The majority of cancers, such as breast cancer, originate from epithelial structures. Highly organiz...
Understanding the cell type-specific molecular mechanisms by which distinct signaling pathways combi...