Expression of canonical PPAR and NF-kB pathway genes in the untreated or PZA-treated infected mouse lungs.

<p>(A). Canonical PPAR and NF-kB pathway map showing interaction of genes in the untreated Mtb-infected mouse lungs at 42 days. The legends for gene symbols are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074082#pone-0074082-g004" target="_blank">Figure 4</a>. Red and green symbols in the networks indicate up-, and down-regulation of SDEG and the gradation in the color intensity of symbols is proportional to their relative expression level. (B). Intensity map of 41 SDEG involved in the PPAR and NF-kB pathways in the untreated and PZA-treated mouse lungs at 42 and 63 days. The scale bar ranges from +3 (up-regulated; red) to –3 (down-regulated; blue).