Antiestrogenic (A) and antiandrogenic activity (B) of 18 bottled waters.

<p>13 waters significantly inhibit estrogen receptor alpha, 16 samples antagonize androgen receptor (★★★p<0.0001, compared to controls with endogenous ligand). The activity was normalized to controls containing 17β-estradiol or testosterone (0% inhibition) and such without (100% inhibition). The results represent three extracts per sample tested in three experiments with eight replicates each.