The effect of Gelam honey on the gene expressions in rats paw tissues.

<p>(<b>A</b>) NF-κB (p65) (<b>B</b>) NF-κB (p50) and (<b>C</b>) IκBα. Rats were pretreated orally with Gelam honey (1 or 2 g/kg of body weight) for 1 or 7 days before inflammation, as induced by carrageenan injection. D.W.: distilled water, Carr: Carrageenan, IND: Indomethacin. Data are presented as the mean ± S.E.M. (n = 6). <b>a</b>: Significantly different (<i>p</i><0.05) from the inflammation group (D.W.+Carr.). <b>b</b>: Significantly different (<i>p</i><0.05) from the Indomethacin group (10 mg/kg IND+Carr.). <b>c</b>: Significantly different (<i>p</i><0.05) between different honey doses at the same time point (1 day or 7 days). <b>d</b>: Significantly different (<i>p</i><0.05) between the same honey dose at different time points (1 day and 7 days).