Mitochondria within the presynaptic boutons in the antennal lobes present structural alterations in <i>PINK1^B9</i>mutants.

<p>Transmission electron microscopy (TEM) images of mitochondria within the olfactory bulbs of WT and <i>PINK1^B9 Drosophila</i>. A: Two mitochondria in a presynaptic bouton of a WT (scale bar = 200 µm). The regular array of mitochondrial cristae (arrowheads) is surrounded by an electron-dense matrix. B: A mitochondrion in a presynaptic bouton of a <i>PINK1^B9</i> mutant (scale bar = 100 µm). The mitochondrion presents a swelling on its external membrane (arrow) and the mitochondrial cristae are highly degenerated (asterisk). C: a conventional mitochondrion in a WT (scale bar = 200 µm). The regular electron-dense matrix surrounds the mitochondrial cristae (asterisk). D: The abnormal mitochondrial morphology in a <i>PINK1^B9</i> mutant. The mitochondrial cristae are fragmented (arrowhead). E: The abnormal mitochondrial morphology in a <i>PINK1^B9</i> mutant (scale bar = 100 µm). Remnants of the mitochondrial cristae are visible within the mitochondrial matrix (scale bar = 100 µm).