<p>∶<b>1).</b> Each spectrum is an average of 36 scans. The figure shows the results of dynamic light scattering analysis as a function of incubation time. Panel C shows hydrodynamic radius of 350 μM insulin, in presence and absence of NK9 at different times of incubation at fibrillation inducing environment. Filled square represents insulin and open circle represents insulin in presence of NK9. Each DLS measurement is an average of 36 scans and the error bar represents the standard deviation of those 36 measurements.</p
Although protein structure has been studied for many decades it remains the case that we cannot stat...
<p>The excitation spectra (em. 303 nm) were obtained before and after 276 nm light continuous exc. (...
<p>Molar ratio of NK9 to insulin is 1∶1. Insulin fibrils were grown at pH 2.6 and temperature 62°C f...
Insulin forms fibrils rich in beta sheets at extreme pHs and temperatures. The fibrils may be identi...
<p>Absorbance profiles at 220 nm from size exclusion chromatography experiments with insulin (350 μM...
<p>Time dependent FT-IR spectra of insulin (2.0 mg/ml in D<sub>2</sub>O) in absence (A) and presence...
abstract: Insulin is an essential peptide hormone that aides in the metabolism of glucose by allowin...
<p>The <i>left plot</i> shows the relation between the fraction of low-binding cellular volume and t...
<p>Error bars correspond to standard deviations of fluorescence intensity calculated for six micropl...
(A) The tendencies of two insulin samples (0.5 mg/mL) were analyzed in the presence of DTT at 40°C. ...
<p>(A) Absorbance spectra obtained before and after 276 nm light continuous exc. (0.25 h, 0.5 h, 0.7...
Tyrosine fluorescence emission spectra of the natively folded and standard insulin. The insulin samp...
<p>(A) Raw NIR spectra data set. Two regions over 1300–1600 nm and 2050–2350 nm were focused on to e...
<p>Fitting parameters and corresponding errors (standard error), and root mean square errors were ob...
<p>(A) Temporal evolution of the ThT fluorescence intensity during incubation of insulin (350 μM) in...
Although protein structure has been studied for many decades it remains the case that we cannot stat...
<p>The excitation spectra (em. 303 nm) were obtained before and after 276 nm light continuous exc. (...
<p>Molar ratio of NK9 to insulin is 1∶1. Insulin fibrils were grown at pH 2.6 and temperature 62°C f...
Insulin forms fibrils rich in beta sheets at extreme pHs and temperatures. The fibrils may be identi...
<p>Absorbance profiles at 220 nm from size exclusion chromatography experiments with insulin (350 μM...
<p>Time dependent FT-IR spectra of insulin (2.0 mg/ml in D<sub>2</sub>O) in absence (A) and presence...
abstract: Insulin is an essential peptide hormone that aides in the metabolism of glucose by allowin...
<p>The <i>left plot</i> shows the relation between the fraction of low-binding cellular volume and t...
<p>Error bars correspond to standard deviations of fluorescence intensity calculated for six micropl...
(A) The tendencies of two insulin samples (0.5 mg/mL) were analyzed in the presence of DTT at 40°C. ...
<p>(A) Absorbance spectra obtained before and after 276 nm light continuous exc. (0.25 h, 0.5 h, 0.7...
Tyrosine fluorescence emission spectra of the natively folded and standard insulin. The insulin samp...
<p>(A) Raw NIR spectra data set. Two regions over 1300–1600 nm and 2050–2350 nm were focused on to e...
<p>Fitting parameters and corresponding errors (standard error), and root mean square errors were ob...
<p>(A) Temporal evolution of the ThT fluorescence intensity during incubation of insulin (350 μM) in...
Although protein structure has been studied for many decades it remains the case that we cannot stat...
<p>The excitation spectra (em. 303 nm) were obtained before and after 276 nm light continuous exc. (...
<p>Molar ratio of NK9 to insulin is 1∶1. Insulin fibrils were grown at pH 2.6 and temperature 62°C f...