<p>(<b>A</b>) Serial gallocynanin stained sections of the L2–L6 region from 90 day old spinal cord from female mice were analysed under light microscopy and motor neurons counted. The bar chart shows the mean motor neuron number ±SEM (n = 3; *p<0.05). (<b>B</b>) Mean survival of male G93A and DBLE mice is shown (n≥11). Overexpression of hHSJ1a had no effect on the lifespan of SOD1<sup>G93A</sup> mice.</p
Plastic changes have been reported in the SOD1-G93A mouse model of amyotrophic lateral sclerosis, a ...
Spinal muscular atrophy (SMA), which is caused by inactivating mutations in the survival motor neuro...
hSOD1 (G93A) transgenic mice develop pathological changes similar to those in patients with familial...
<p>(<b>A</b>) Typical examples of motor unit traces are shown from the EDL muscle of WT, hHSJ1a, G93...
<p>(<b>A</b>) Representative Western blot showing total levels of HSJ1 expression in G93A and DBLE t...
<p>(<b>A</b>) Representative Western blot with anti-SOD1 (C4F6) of spinal cord lysates from male tra...
<p>Motor neuron counts were performed in the cervical (<b>A</b>) and lumbar (<b>B</b>) ventral horns...
<p>(<b>A</b>) Immunohistochemistry with SEDI anti-SOD1 antibody on 120 day lumbar spinal cord from f...
In the inherited childhood neuromuscular disease spinal muscular atrophy (SMA), lower motor neuron d...
<p>(A) NeuN-stained cross-sections of the spinal cord at the level L3 to L5. Non-treated controls (S...
Spinal muscular atrophy results from diminished levels of survival motor neuron (SMN) protein in spi...
Spinal muscular atrophy results from diminished levels of survival motor neuron (SMN) protein in spi...
International audienceHuntington's disease (HD) is an autosomal dominant disease that develops in mi...
Lower motor function was evaluated in (A) plantar and (B) tibialis anterior (TA) muscles at 8–16 wee...
<p><b>A:</b> SOD1 mice were implanted with either a DHT-filled or an empty silastic (control) tube a...
Plastic changes have been reported in the SOD1-G93A mouse model of amyotrophic lateral sclerosis, a ...
Spinal muscular atrophy (SMA), which is caused by inactivating mutations in the survival motor neuro...
hSOD1 (G93A) transgenic mice develop pathological changes similar to those in patients with familial...
<p>(<b>A</b>) Typical examples of motor unit traces are shown from the EDL muscle of WT, hHSJ1a, G93...
<p>(<b>A</b>) Representative Western blot showing total levels of HSJ1 expression in G93A and DBLE t...
<p>(<b>A</b>) Representative Western blot with anti-SOD1 (C4F6) of spinal cord lysates from male tra...
<p>Motor neuron counts were performed in the cervical (<b>A</b>) and lumbar (<b>B</b>) ventral horns...
<p>(<b>A</b>) Immunohistochemistry with SEDI anti-SOD1 antibody on 120 day lumbar spinal cord from f...
In the inherited childhood neuromuscular disease spinal muscular atrophy (SMA), lower motor neuron d...
<p>(A) NeuN-stained cross-sections of the spinal cord at the level L3 to L5. Non-treated controls (S...
Spinal muscular atrophy results from diminished levels of survival motor neuron (SMN) protein in spi...
Spinal muscular atrophy results from diminished levels of survival motor neuron (SMN) protein in spi...
International audienceHuntington's disease (HD) is an autosomal dominant disease that develops in mi...
Lower motor function was evaluated in (A) plantar and (B) tibialis anterior (TA) muscles at 8–16 wee...
<p><b>A:</b> SOD1 mice were implanted with either a DHT-filled or an empty silastic (control) tube a...
Plastic changes have been reported in the SOD1-G93A mouse model of amyotrophic lateral sclerosis, a ...
Spinal muscular atrophy (SMA), which is caused by inactivating mutations in the survival motor neuro...
hSOD1 (G93A) transgenic mice develop pathological changes similar to those in patients with familial...