Specificity of the prophylactic vaccination.

<p>A: Schematic diagram of the prophylactic vaccination. Two groups of BALB/c mice (n = 7) were immunized i.m. with either 10⁷IU/mouse MVA-HKenv or 10⁸ IU/mouse MVA on day 0 and day 21. The mice were injected i.v. with 5×10⁵ RLZ-HKenv cells on day 33 and sacrificed on day 69. The lungs were removed and stained with X-Gal. B: Lungs of miceThe lungs of the animals were excised and stained with X-gal. Tumor nodules are visible by blue staining of the cells. C: Analysis of tumor nodules. The number of lung tumor nodules was counted on the surface of the lungs and data for each mouse are shown. The p-value of 0.015 shows significance.