ROC curves and corresponding AUCs for new-T2DM.

<div><p>The AUC in an established conventional model was 0.753 (95% CI, 0.679 to 0.827), and that in a model with plasma HO-1 concentration plus the established conventional model was 0.813 (95% CI, 0.750 to 0.876). After circulating miRNA-146a levels were introduced, the AUC was 0.844 (95% CI, 0.785 to 0.903). In addition, the AUC of all parameters included was 0.865 (95% CI, 0.813 to 0.917); <i>P</i> = 0.0009 for the differences of the above AUCs. The established conventional model here consists of age, sex, BMI, smoking, alcohol drinking, hypertension, and family history of diabetes, TC, TG, HDL-C and LDL-C.</p> <p>Abbreviations: AUC, area under the curve; BMI, body mass index; CI, confidence interval; HDL-C, high-density lipoprotein-cholesterol; HO-1, heme oxygenase-1; LDL-C, low-density lipoprotein-cholesterol; new-T2DM, newly diagnosed type 2 diabetes mellitus; ROC, receiver operating characteristic; TC, total cholesterol; TG, triglycerides.</p>