Plasma viral loads following primary infection and superinfection in each monkey.

<p>(<b>A</b>) Kinetics of plasma viral loads of twelve monkeys with a SHIV_SF162P3 primary infection (black lines) followed by SHIV-1157ipd3N4 superinfection (red lines). Total viral loads of twelve monkeys after superinfection are shown by black dashed lines. The area under the curve (AUC) of SHIV_SF162P3 viremia of each monkey for the acute infection (0–130 days) was indicated. (<b>B</b>) Kinetics of plasma SHIV-1157ipd3N4 loads in twelve monkeys after superinfection at each time point. The monkeys with plasma SHIV-1157ipd3N4 loads more than 10³ copies per ml (blue dashed line) were defined as superinfection-sensitive group (SIS) and those less than 10³ copies per ml as superinfection-resistant group (SIR). (<b>C</b>) Kinetics of the average viral load of SHIV-1157ipd3N4 in SIS (red line) and SIR monkeys (black line) (Mann-Whitney U test, <i>*p<0.05</i>). Viral loads are shown as log10 copies of viral load/ml of plasma and the limits of detection are 100 copies per ml (black dotted lines).