<p>A) Fasting blood glucose levels of young and old, WT and <i>Id2−/−</i> mice (ANOVA: genotype, P<0.01; age, P<0.001; interaction, n.s.). B). Fasting insulin levels of young and old, WT and <i>Id2−/−</i> mice (genotype, P<0.001; age, P<0.05; interaction, n.s.). Values shown represent mean ± SEM. *p<0.05, **p<0.01 and ***p<0.001.</p
<p>(A–E) Whole body insulin sensitivity after intra-peritoneal insulin injection (0.75 U/kg) and qua...
<p>Mice fed with a high AGE diet (n = 5) or a regular AGE diet (n = 5) for 26 and 39 weeks were anal...
<p>(A) FVB/NJ-<i>Ins2</i><sup>+/C96Y</sup> mice developed sustained hyperglycemia by 4 weeks of age,...
<p>(A) Random blood glucose levels in 2–16 weeks of age (n = 10–12). (B) Fasting blood glucose level...
<p>A) Glucose tolerance test (GTT) of young male WT and <i>Id2−/−</i> mice (RM-ANOVA: time (T), P<0....
<p>(A) Glucose tolerance tests (GTT) were performed in different groups of mice at different ages (4...
<p>A. RIIβ<sup>−/−</sup> blood glucose levels were slightly lower than WT for both old males and fem...
<p>Data shown as the mean ± SEM (n = 4 per group). *, p<0.05 compared to 0 minute insulin level.</p
<p>Fasting blood glucose (FBG), random blood glucose (RBG), fasting serum insulin (FSI), and random ...
<p>(A–E) Blood glucose was measured after an overnight fast (16 hr) or in random-fed states at the i...
<p>(a) Body weight of db/db and db/+ mice. (b) Fasting blood glucose levels of db/db and db/+ mice. ...
<p>Different groups of mice at different ages (4, 8, 12, 16 and 20-months old) were fed with regular...
<p>(A,B) Fasting blood glucose (A) and insulin levels (B) in male non-progressing mice 30 weeks of a...
<p>A) Weight increases significantly with age in <i>ob/ob</i>-luc mice consistent with the original ...
(A) Blood glucose quantification in 2 and 6 months old mice measured in overnight fasted and fed sta...
<p>(A–E) Whole body insulin sensitivity after intra-peritoneal insulin injection (0.75 U/kg) and qua...
<p>Mice fed with a high AGE diet (n = 5) or a regular AGE diet (n = 5) for 26 and 39 weeks were anal...
<p>(A) FVB/NJ-<i>Ins2</i><sup>+/C96Y</sup> mice developed sustained hyperglycemia by 4 weeks of age,...
<p>(A) Random blood glucose levels in 2–16 weeks of age (n = 10–12). (B) Fasting blood glucose level...
<p>A) Glucose tolerance test (GTT) of young male WT and <i>Id2−/−</i> mice (RM-ANOVA: time (T), P<0....
<p>(A) Glucose tolerance tests (GTT) were performed in different groups of mice at different ages (4...
<p>A. RIIβ<sup>−/−</sup> blood glucose levels were slightly lower than WT for both old males and fem...
<p>Data shown as the mean ± SEM (n = 4 per group). *, p<0.05 compared to 0 minute insulin level.</p
<p>Fasting blood glucose (FBG), random blood glucose (RBG), fasting serum insulin (FSI), and random ...
<p>(A–E) Blood glucose was measured after an overnight fast (16 hr) or in random-fed states at the i...
<p>(a) Body weight of db/db and db/+ mice. (b) Fasting blood glucose levels of db/db and db/+ mice. ...
<p>Different groups of mice at different ages (4, 8, 12, 16 and 20-months old) were fed with regular...
<p>(A,B) Fasting blood glucose (A) and insulin levels (B) in male non-progressing mice 30 weeks of a...
<p>A) Weight increases significantly with age in <i>ob/ob</i>-luc mice consistent with the original ...
(A) Blood glucose quantification in 2 and 6 months old mice measured in overnight fasted and fed sta...
<p>(A–E) Whole body insulin sensitivity after intra-peritoneal insulin injection (0.75 U/kg) and qua...
<p>Mice fed with a high AGE diet (n = 5) or a regular AGE diet (n = 5) for 26 and 39 weeks were anal...
<p>(A) FVB/NJ-<i>Ins2</i><sup>+/C96Y</sup> mice developed sustained hyperglycemia by 4 weeks of age,...