<i>Plasmodium</i> infection intensity in aseptic mosquitoes after depleting <i>SRPN7</i> or <i>CLIPC2</i> through RNAi gene silencing.

<p>(A) <i>P. falciparum</i> infection intensity following RNAi-mediated depletion of <i>SRPN7</i> (Dunn's post test, p<0.05) and <i>CLIPC2</i> (Dunn's post test, p>0.05). (B) <i>P. falciparum</i> infection intensity following double RNAi-mediated depletion of <i>SRPN7</i> and <i>CLIPC2</i> (p = 0.87). (C) <i>P. berghei</i> infection intensity following RNAi-mediated depletion of <i>SRPN7</i> and <i>CLIPC2</i> (Kruskal-Wallis test p = 0.42). Circles represent the number of oocysts from a single midgut; horizontal black bars represent the median oocysts in each RNAi treatment. Three independent biological replicates were pooled, and significance was determined by a Kruskal-Wallis test followed by Dunn's post-test in the case of multiple comparisons. Statistical analysis of the double RNAi knockdown was performed using a Mann-Whitney test. RNAi treatments were compared to <i>dsGFP</i>-injected control mosquitoes.