Conceptual model of the spread of a vector-borne pathogen during favourable period with reactivation of viremia during persistent infection in hosts.

<p>Squares represent the health states of hosts, circle those of vectors. Solid lines represent transitions between health statuses, dashed lines represent the host-to-vector transmission (when a susceptible vector (<i>SV</i>) bites an infectious host (<i>IH</i>) and becomes exposed but not yet infectious <i>(EV)</i>), and dotted lines represent the vector-to-host transmission (when an infectious vector (<i>IV</i>) bites a susceptible host (<i>SH</i>) which becomes infectious (<i>IH</i>)). In orange, modifications in model due to the mechanism compared with the conceptual model in favourable period without any mechanism (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074213#pone-0074213-g001" target="_blank">Figure 1</a>).