<p>Tubulin was incubated with the compounds ((A), ESE-16 (B), ESE-15-one (C) and EMBS (D)), as described in the methods section. This assay showed that ESE-16 had a pronounced effect comparable with that of colchicine.</p
<p>(A) Tubulin assembly study. Tubulin (12 µM) was polymerized separately in the presence of (0 −200...
<p>Cells were treated with or without 2.5 μM MPT0B169 for 24 h. The polymer and free form of tubulin...
<p>(A) MPT0B214 inhibits microtubule assembly in vitro. MAP-rich tubulin was incubated at 37°C in th...
<p>(A) <i>In-vitro</i> tubulin polymerization assays were used to test the effect of the 212 mitotic...
<p>Purified tubulin polymerization was quantitated by turbidimetry measurement at 350 nm with or wit...
<p>PC12 cells were incubated with 10 μM ASN for 48 h. SB-216763, Colchicine and Taxol were used as G...
<p><b>A</b>) As a reference, 1 µM tubulysin A was added to a preparation of 10 µM tubulin, and the a...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
<p>In vitro polymerization of tubulin, purified from pig brain, in the presence of 0μM (●), 0.25μM (...
AbstractTaxol-induced assembly of purified tubulin is not inhibited by the colchicine analogue 2-met...
Purpose: To determine whether inhibitors of microtubule assembly inhibit polymerization induced by d...
The polymerization ofmicrotubules in vitro exhibits many of the properties of a nucleated helical po...
<p>Effects of LJK-11 (250 µM), colchicines (10 µM), nocodazole (10 µM), or Taxol (10 µM) on bovine b...
AbstractBinding of two colchicine analogues, desacetamidocolchicine and 2-methoxy-5-(2′,3′,4′-trimet...
<p>Tubulin was pre-incubated for 1 min with <b>10s</b> at 2 μM, 10 μM, 25 μM and 50 μM, CA-4 at 0.5 ...
<p>(A) Tubulin assembly study. Tubulin (12 µM) was polymerized separately in the presence of (0 −200...
<p>Cells were treated with or without 2.5 μM MPT0B169 for 24 h. The polymer and free form of tubulin...
<p>(A) MPT0B214 inhibits microtubule assembly in vitro. MAP-rich tubulin was incubated at 37°C in th...
<p>(A) <i>In-vitro</i> tubulin polymerization assays were used to test the effect of the 212 mitotic...
<p>Purified tubulin polymerization was quantitated by turbidimetry measurement at 350 nm with or wit...
<p>PC12 cells were incubated with 10 μM ASN for 48 h. SB-216763, Colchicine and Taxol were used as G...
<p><b>A</b>) As a reference, 1 µM tubulysin A was added to a preparation of 10 µM tubulin, and the a...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
<p>In vitro polymerization of tubulin, purified from pig brain, in the presence of 0μM (●), 0.25μM (...
AbstractTaxol-induced assembly of purified tubulin is not inhibited by the colchicine analogue 2-met...
Purpose: To determine whether inhibitors of microtubule assembly inhibit polymerization induced by d...
The polymerization ofmicrotubules in vitro exhibits many of the properties of a nucleated helical po...
<p>Effects of LJK-11 (250 µM), colchicines (10 µM), nocodazole (10 µM), or Taxol (10 µM) on bovine b...
AbstractBinding of two colchicine analogues, desacetamidocolchicine and 2-methoxy-5-(2′,3′,4′-trimet...
<p>Tubulin was pre-incubated for 1 min with <b>10s</b> at 2 μM, 10 μM, 25 μM and 50 μM, CA-4 at 0.5 ...
<p>(A) Tubulin assembly study. Tubulin (12 µM) was polymerized separately in the presence of (0 −200...
<p>Cells were treated with or without 2.5 μM MPT0B169 for 24 h. The polymer and free form of tubulin...
<p>(A) MPT0B214 inhibits microtubule assembly in vitro. MAP-rich tubulin was incubated at 37°C in th...
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