<i>Kaiso<sup>Tg</sup></i><sup>/+</sup> mice display decreased HES-1 expression in the small intestine.
- Roopali Chaudhary (454981)
- Christina C. Pierre (114513)
- Kyster Nanan (454982)
- Daria Wojtal (454983)
- Simona Morone (141356)
- Christopher Pinelli (454984)
- Geoffrey A. Wood (454985)
- Sylvie Robine (351514)
- Juliet M. Daniel (114527)
Publication date
September 2013
DOIAbstract
<p>Both Non-Tg and <i>Kaiso<sup>Tg</sup></i><sup>/+</sup> tissues displayed nuclear HES-1 expression in the crypts of the small intestine, however <i>Kaiso<sup>Tg</sup></i><sup>/+</sup> tissue displays significantly decreased HES-1 expression in the villi. Quantitative RT-PCR showed a significant decrease in HES-1 expression in <i>Kaiso<sup>Tg</sup></i><sup>/+</sup> mice. Values were first normalized to the GAPDH housekeeping gene, followed by normalizing to non-Tg HES-1 expression (** represents p<0.05).</p
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