<p>The top 32 RNA markers (Table 1) from IWAT are represented in the clustergram (see Figure S2 for EWAT and RPWAT). Plotted are the logRatio values on a scale of +/- 0.6 (+/- 4 fold) with magenta and cyan signifying up- and down-regulated genes, respectively. Each row is the average of up to 5 animals for that treatment group. Gene names are shown below the clustergram. Native = WT FGF21; PEG-L and PEG-H = PEG30-FGF21 Q108 at 0.75 and 2.5 mg/kg, respectively; and 2d and 5d correspond to number of days of treatment.</p
<p>(A) Fasting plasma levels of fibroblast growth factor (FGF) 21 are increased 2-fold in HIV subjec...
<p>The horizontal axis is the sample names and the right vertical axis represents the genes. The lef...
<p>Thirty age- and weight-matched mice (2×3×5) were fasted for 24 hrs with water freely available, a...
<p>(<b>A</b>) FGF21 mRNA was measured by qRT-PCR relative to 18S RNA levels in multiple tissues of t...
FGF21 is a novel secreted protein with robust anti-diabetic, anti-obesity, and anti-atherogenic acti...
FGF21 is a novel secreted protein with robust anti-diabetic, anti-obesity, and anti-atherogenic acti...
The fibroblast growth factor 21 (FGF21) is a member of the FGF superfamily that now comprises 22 mem...
<p>Animals were treated with HFD at week 4. Gene expression was assessed by real-time RT-PCR. Data a...
<p>Panel A-F are WJMSCs on DWJM with A) Cell adhesion genes, B) Chondrogenic genes, C) Adipogenic ge...
<p>Gene expression of <i>Cyp27a1</i> <b>(A)</b>, <i>Cyp2r1</i> <b>(B)</b>, <i>Cyp27b1</i> <b>(C)</b>...
<p><b>(A)</b> Differential gene expression by Affymetrix Human Genome U219 expression arrays in omen...
<p>(A) The mRNA level of <i>fgf21</i> in the liver. (B) The mRNA level of <i>fgf21</i> in adipose ti...
<p>C57BL/6 mice on chow diet were treated with a single dose of vehicle or PEG30-FGF21 Q108 at one o...
<p>(A) PPAR<i>alpha</i> expression; (B) PPAR<i>gamma</i> expression; (C) Adiponectin expression; (D)...
<p>The relative levels of mRNA were measured in eight tissues from thirteen-lined ground squirrels w...
<p>(A) Fasting plasma levels of fibroblast growth factor (FGF) 21 are increased 2-fold in HIV subjec...
<p>The horizontal axis is the sample names and the right vertical axis represents the genes. The lef...
<p>Thirty age- and weight-matched mice (2×3×5) were fasted for 24 hrs with water freely available, a...
<p>(<b>A</b>) FGF21 mRNA was measured by qRT-PCR relative to 18S RNA levels in multiple tissues of t...
FGF21 is a novel secreted protein with robust anti-diabetic, anti-obesity, and anti-atherogenic acti...
FGF21 is a novel secreted protein with robust anti-diabetic, anti-obesity, and anti-atherogenic acti...
The fibroblast growth factor 21 (FGF21) is a member of the FGF superfamily that now comprises 22 mem...
<p>Animals were treated with HFD at week 4. Gene expression was assessed by real-time RT-PCR. Data a...
<p>Panel A-F are WJMSCs on DWJM with A) Cell adhesion genes, B) Chondrogenic genes, C) Adipogenic ge...
<p>Gene expression of <i>Cyp27a1</i> <b>(A)</b>, <i>Cyp2r1</i> <b>(B)</b>, <i>Cyp27b1</i> <b>(C)</b>...
<p><b>(A)</b> Differential gene expression by Affymetrix Human Genome U219 expression arrays in omen...
<p>(A) The mRNA level of <i>fgf21</i> in the liver. (B) The mRNA level of <i>fgf21</i> in adipose ti...
<p>C57BL/6 mice on chow diet were treated with a single dose of vehicle or PEG30-FGF21 Q108 at one o...
<p>(A) PPAR<i>alpha</i> expression; (B) PPAR<i>gamma</i> expression; (C) Adiponectin expression; (D)...
<p>The relative levels of mRNA were measured in eight tissues from thirteen-lined ground squirrels w...
<p>(A) Fasting plasma levels of fibroblast growth factor (FGF) 21 are increased 2-fold in HIV subjec...
<p>The horizontal axis is the sample names and the right vertical axis represents the genes. The lef...
<p>Thirty age- and weight-matched mice (2×3×5) were fasted for 24 hrs with water freely available, a...