Synthesis of Highly Substituted 4H‑Pyrido[1,2‑a]pyrimidines via a One-Pot Three-Component Condensation Reaction

A Sustainable Multicomponent Pyrimidine Synthesis

Nicklas Deibl (1510711)
Kevin Ament (1510708)
Rhett Kempe (1510705)

October 2015

Since alcohols are accessible from indigestible biomass (lignocellulose), the development of novel p...

One-pot synthesis of new Pyrido [2,3-d] Pyrimidine derivatives under ultrasonic irradiation using organo catalyst 4-Dimethylaminopyridine (DMAP)

Parrey Imtiyaz Rasool
Hashmi Athar Adil

December 2016

The one-pot synthesis of pyrido[2,3-d] pyrimidine derivatives has been reported via Knoevenagel-Mich...

Route to Highly Substituted Pyridines

Justin A. Hilf (1545928)
Michael S. Holzwarth (2101342)
Scott D. Rychnovsky (1335972)

August 2016

Pyridine rings are common structural motifs found in a number of biologically active compounds, incl...

Synthesis of Highly Substituted 4H‑Pyrido[1,2‑a]pyrimidines via a One-Pot Three-Component Condensation Reaction

Kai Yang (73590)
Jinbao Xiang (1666171)
Guochen Bao (1915291)
Qun Dang (1666174)
Xu Bai (394384)

September 2013

A one-pot three-component reaction, involving condensation of 2-aminopyridines, aldehydes, and keton...

Synthesis of some Substituted Pyrido[1,2-a]pyrimidin-4-ones and 1,8-Naphthyridines.

P.L. Ferrarini
C. Mori
O. Livi
G. Biagi
Marini A

January 1983

The substituted 4H-pyrido[1, 2-a]pyrimidin-4-ones (I) were obtained by the condensation of substitut...

Three-Component Coupling of Aldehydes, 2‑Aminopyridines, and Diazo Esters via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrido[1,2‑a]pyrimidin-4-ones

Gia L. Hoang (1310700)
Adam J. Zoll (6493610)
Jonathan A. Ellman (610362)

March 2019

Imines formed in situ from 2-aminopyridines and aldehydes undergo Rh(III)-catalyzed imidoyl C–H act...

One-pot, three-component, catalyst-free synthesis of novel derivatives of pyrido-[2,3-d]pyrimidines under ultrasonic irradiations

Azam Barghi-Lish (2815528)
Sina Farzaneh (2815525)
Manouchehr Mamaghani (703230)

July 2016

Novel derivatives of pyrido-[2,3-d] pyrimidines were synthesized via an efficient and cata...

A “Neat” Synthesis of Substituted 2-Hydroxy-pyrido[1,2-a]pyrimidin-4-ones

Gregory, Gaube
James, Mutter
David, Leitch

September 2023

We report the synthesis of a series of substituted 2-hydroxy-pyrido[1,2-a]pyrimidin-4-ones through s...

Cyclocondensation of cyanoketene dithioacetal with 2-aminopyridine: Synthesis of pyrido [1, 2-a]pyrimidines

Singh, Okram Mukherjee
Ahmed, Mohd Farooque

July 2004

1561-1564The cyanoketene dithioacetal 1 on treatment with 2-aminopyridine gives 2-ethoxy/2-methylth...

Metal-Free Assemblage of Four C−N and Two C−C Bonds via a Cascade Five Component Diastereoselective Synthesis of Pyrido[1,2-a]Pyrimidines

M Heravi
Rezvanian, A.
Alinaghian, F.

November 2018

An efficient heteroannulation synthesis of N-fused, pyrido[1,2-a]pyrimidines was successfully achiev...

Synthesis of pyridopyrimidine derivatives based on benzenesulfonyl acetonitrile compounds via a one-pot sequential four-component domino reaction and microwave-mediated molecular cyclization

Zhengyu Zhang (172753)
Ailin Yuan (5944910)
Chunling Zheng (5944913)

December 2018

A concise, rapid and highly efficient method for the one-pot synthesis of novel pyridopyrimidine der...

An efficient, Method for the Synthesis of 4H-Pyrido-[1, 2]-Pyrimidine Derivatives and their anticancer activity

Jyothi Vantikommu*, Sadanandam Palle

January 2022

ABSTRACT A library of 4H-pyrido-[1,2]-pyrimidine derivatives were synthesised via one pot three com...

Efficient One-Pot, Three-Component Synthesis of a Library of Pyrrolo[1,2-c]pyrimidine Derivatives

Emilian Georgescu (2114401)
Florentina Georgescu (2114404)
Marcel M. Popa (2114407)
Constantin Draghici (2114413)
Laszlo Tarko (2114410)
Florea Dumitrascu (2059588)

February 2012

Herein is reported a simple and efficient one-pot three-component synthesis of pyrrolo[1,2-c...

A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation

Ramadan Mekheimer

March 2018

A convenient, fast and environmentally benign procedure for the synthesis of a new series of highly ...

Synthesis of Pyridopyrimidines by Palladium-Catalyzed Isocyanide Insertion

Estévez, Verónica
Van Baelen, Gitte
Lentferink, Babette H.
Vlaar, Tjøstil
Janssen, Elwin
Maes, Bert U.W.
Orru, Romano V.A.
Ruijter, Eelco

January 2014

A new synthetic approach to 4-aminopyrido[2,3-d]pyrimidines and 4-aminopyrido[3,2-d]pyrimidines base...

A Sustainable Multicomponent Pyrimidine Synthesis

Nicklas Deibl (1510711)
Kevin Ament (1510708)
Rhett Kempe (1510705)

October 2015

Since alcohols are accessible from indigestible biomass (lignocellulose), the development of novel p...

One-pot synthesis of new Pyrido [2,3-d] Pyrimidine derivatives under ultrasonic irradiation using organo catalyst 4-Dimethylaminopyridine (DMAP)

Parrey Imtiyaz Rasool
Hashmi Athar Adil

December 2016

The one-pot synthesis of pyrido[2,3-d] pyrimidine derivatives has been reported via Knoevenagel-Mich...

Route to Highly Substituted Pyridines

Justin A. Hilf (1545928)
Michael S. Holzwarth (2101342)
Scott D. Rychnovsky (1335972)

August 2016

Pyridine rings are common structural motifs found in a number of biologically active compounds, incl...

Synthesis of Highly Substituted 4H‑Pyrido[1,2‑a]pyrimidines via a One-Pot Three-Component Condensation Reaction

Kai Yang (73590)
Jinbao Xiang (1666171)
Guochen Bao (1915291)
Qun Dang (1666174)
Xu Bai (394384)

September 2013

A one-pot three-component reaction, involving condensation of 2-aminopyridines, aldehydes, and keton...

Synthesis of some Substituted Pyrido[1,2-a]pyrimidin-4-ones and 1,8-Naphthyridines.

P.L. Ferrarini
C. Mori
O. Livi
G. Biagi
Marini A

January 1983

The substituted 4H-pyrido[1, 2-a]pyrimidin-4-ones (I) were obtained by the condensation of substitut...

Three-Component Coupling of Aldehydes, 2‑Aminopyridines, and Diazo Esters via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrido[1,2‑a]pyrimidin-4-ones

Gia L. Hoang (1310700)
Adam J. Zoll (6493610)
Jonathan A. Ellman (610362)

March 2019

Imines formed in situ from 2-aminopyridines and aldehydes undergo Rh(III)-catalyzed imidoyl C–H act...

One-pot, three-component, catalyst-free synthesis of novel derivatives of pyrido-[2,3-d]pyrimidines under ultrasonic irradiations

Azam Barghi-Lish (2815528)
Sina Farzaneh (2815525)
Manouchehr Mamaghani (703230)

July 2016

Novel derivatives of pyrido-[2,3-d] pyrimidines were synthesized via an efficient and cata...

A “Neat” Synthesis of Substituted 2-Hydroxy-pyrido[1,2-a]pyrimidin-4-ones

Gregory, Gaube
James, Mutter
David, Leitch

September 2023

We report the synthesis of a series of substituted 2-hydroxy-pyrido[1,2-a]pyrimidin-4-ones through s...

Cyclocondensation of cyanoketene dithioacetal with 2-aminopyridine: Synthesis of pyrido [1, 2-a]pyrimidines

Singh, Okram Mukherjee
Ahmed, Mohd Farooque

July 2004

1561-1564The cyanoketene dithioacetal 1 on treatment with 2-aminopyridine gives 2-ethoxy/2-methylth...

Metal-Free Assemblage of Four C−N and Two C−C Bonds via a Cascade Five Component Diastereoselective Synthesis of Pyrido[1,2-a]Pyrimidines

M Heravi
Rezvanian, A.
Alinaghian, F.

November 2018

An efficient heteroannulation synthesis of N-fused, pyrido[1,2-a]pyrimidines was successfully achiev...

Synthesis of pyridopyrimidine derivatives based on benzenesulfonyl acetonitrile compounds via a one-pot sequential four-component domino reaction and microwave-mediated molecular cyclization

Zhengyu Zhang (172753)
Ailin Yuan (5944910)
Chunling Zheng (5944913)

December 2018

A concise, rapid and highly efficient method for the one-pot synthesis of novel pyridopyrimidine der...

An efficient, Method for the Synthesis of 4H-Pyrido-[1, 2]-Pyrimidine Derivatives and their anticancer activity

Jyothi Vantikommu*, Sadanandam Palle

January 2022

ABSTRACT A library of 4H-pyrido-[1,2]-pyrimidine derivatives were synthesised via one pot three com...

Efficient One-Pot, Three-Component Synthesis of a Library of Pyrrolo[1,2-c]pyrimidine Derivatives

Emilian Georgescu (2114401)
Florentina Georgescu (2114404)
Marcel M. Popa (2114407)
Constantin Draghici (2114413)
Laszlo Tarko (2114410)
Florea Dumitrascu (2059588)

February 2012

Herein is reported a simple and efficient one-pot three-component synthesis of pyrrolo[1,2-c...

A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation

Ramadan Mekheimer

March 2018

A convenient, fast and environmentally benign procedure for the synthesis of a new series of highly ...

Synthesis of Pyridopyrimidines by Palladium-Catalyzed Isocyanide Insertion

Estévez, Verónica
Van Baelen, Gitte
Lentferink, Babette H.
Vlaar, Tjøstil
Janssen, Elwin
Maes, Bert U.W.
Orru, Romano V.A.
Ruijter, Eelco

January 2014

A new synthetic approach to 4-aminopyrido[2,3-d]pyrimidines and 4-aminopyrido[3,2-d]pyrimidines base...

A Sustainable Multicomponent Pyrimidine Synthesis

Nicklas Deibl (1510711)
Kevin Ament (1510708)
Rhett Kempe (1510705)

October 2015

Since alcohols are accessible from indigestible biomass (lignocellulose), the development of novel p...

One-pot synthesis of new Pyrido [2,3-d] Pyrimidine derivatives under ultrasonic irradiation using organo catalyst 4-Dimethylaminopyridine (DMAP)

Parrey Imtiyaz Rasool
Hashmi Athar Adil

December 2016

The one-pot synthesis of pyrido[2,3-d] pyrimidine derivatives has been reported via Knoevenagel-Mich...

Route to Highly Substituted Pyridines

Justin A. Hilf (1545928)
Michael S. Holzwarth (2101342)
Scott D. Rychnovsky (1335972)

August 2016

Pyridine rings are common structural motifs found in a number of biologically active compounds, incl...

Synthesis of Highly Substituted 4<i>H</i>‑Pyrido[1,2‑<i>a</i>]pyrimidines via a One-Pot Three-Component Condensation Reaction

Abstract

Extracted data

Synthesis of Highly Substituted 4<i>H</i>‑Pyrido[1,2‑<i>a</i>]pyrimidines via a One-Pot Three-Component Condensation Reaction

Abstract

Extracted data

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