Graph showing annualised and normalised rates of change for different aspects of disease.

<p>Green squares are the change in scores for the Addenbrookes Cognitive Examination Revised, green triangles are rates of change for mu (reciprocal latency), purple squares are the change in scores for the Unified Parkinson’s Disease Rating Scale (UPDRS) motor subsection and the purple triangles are the change in scores for the PSP rating scale (PSPRS). The horizontal black lines are the mean rate of change for each test. Values below the x axis represent worsening of patients’ conditions and those above the x axis are improving.