Antibodies targeting region 3–5 of EBA-140 also mediate cross-strain protection against <i>P. falciparum</i>
- Julie Healer (37804)
- Jennifer K. Thompson (456713)
- David T. Riglar (132222)
- Danny W. Wilson (136823)
- Yu-H.C. Chiu (456714)
- Kazutoyo Miura (35285)
- Lin Chen (54305)
- Anthony N. Hodder (148027)
- Carole A. Long (35289)
- Diana S. Hansen (265526)
- Jake Baum (132234)
- Alan F. Cowman (136852)
Publication date
September 2013
DOIAbstract
<p>IgG purified from immune rabbit serum was tested in GIA against 3D7, W2mef and FCR3 strains. No inhibition was observed against EBA-140 knock out parasites. Highest GIA levels were against the homologous strain at 2 mg/ml. Error bars represent SEM (One cycle assay).</p
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