IFN-γ secretion in response to secreted, latent, and reactivation Mtb antigens in active TB and LTBI subjects, from five African sites.

<p>IFN-γ ELISA was performed on supernatants collected after 7-day antigen stimulation of diluted blood from TB cases (grey) and TST⁺ (LTBI) controls (white) from five sites in Africa. Line indicates median, whiskers indicate 5–95% range and dots indicate outliers. Data were analysed by Mann-Whitney U-test within sites for HIV^– and/or HIV⁺ subjects. Significant differences are indicated: *=p<0.05; **=p<0.01; ***=P<0.001.